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    Apr 23, 2021
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    Nifurtimox-Eflornithine Combination Therapy for Second-stage Gambiense Human African Trypanosomiasis: Médecins Sans Frontières experience in the Democratic Republic of the Congo

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    Authors
    Alirol, E
    Schrumpf, D
    Amici Heradi, J
    Riedel, A
    de Patoul, C
    Quere, M
    Chappuis, F
    Affiliation
    Division of International and Humanitarian Medicine, University Hospitals of Geneva, Switzerland. emilie.alirol@hcuge.ch
    Issue Date
    2012-11-09
    
    Metadata
    Show full item record
    Journal
    Clinical Infectious Diseases
    Abstract
    Existing diagnostic and treatment tools for human African trypanosomiasis (HAT) are limited. The recent development of nifurtimox-eflornithine combination therapy (NECT) has brought new hopes for patients in the second stage. While NECT has been rolled out in most endemic countries, safety data are scarce and derive only from clinical trials. The World Health Organization (WHO) coordinates a pharmacovigilance program to collect additional data on NECT safety and efficacy. We report here the results of 18 months of experience of NECT use in treatment centers run by Médecins Sans Frontières in the Democratic Republic of the Congo (DRC).
    Publisher
    Oxford University Press
    URI
    http://hdl.handle.net/10144/303511
    DOI
    10.1093/cid/cis886
    PubMed ID
    23074318
    Additional Links
    http://cid.oxfordjournals.org//cgi/reprint/56/2/195?ijkey=n6iCHos9f2/bE&keytype=ref&siteid=cid
    Language
    en
    Description
    To access this article, click on "Additional Links"
    ISSN
    1537-6591
    ae974a485f413a2113503eed53cd6c53
    10.1093/cid/cis886
    Scopus Count
    Collections
    Trypanosomiasis/Sleeping Sickness

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