Nifurtimox-Eflornithine Combination Therapy for Second-stage Gambiense Human African Trypanosomiasis: Médecins Sans Frontières experience in the Democratic Republic of the Congo
Affiliation
Division of International and Humanitarian Medicine, University Hospitals of Geneva, Switzerland. emilie.alirol@hcuge.chIssue Date
2012-11-09
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Clinical Infectious DiseasesAbstract
Existing diagnostic and treatment tools for human African trypanosomiasis (HAT) are limited. The recent development of nifurtimox-eflornithine combination therapy (NECT) has brought new hopes for patients in the second stage. While NECT has been rolled out in most endemic countries, safety data are scarce and derive only from clinical trials. The World Health Organization (WHO) coordinates a pharmacovigilance program to collect additional data on NECT safety and efficacy. We report here the results of 18 months of experience of NECT use in treatment centers run by Médecins Sans Frontières in the Democratic Republic of the Congo (DRC).Publisher
Oxford University PressPubMed ID
23074318Additional Links
http://cid.oxfordjournals.org//cgi/reprint/56/2/195?ijkey=n6iCHos9f2/bE&keytype=ref&siteid=cidLanguage
enDescription
To access this article, click on "Additional Links"ISSN
1537-6591ae974a485f413a2113503eed53cd6c53
10.1093/cid/cis886
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