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    Mar 04, 2021
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    Diphtheria outbreak with high mortality in northeastern Nigeria

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    Besa et al. - 2013 - Diphtheria ...
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    Authors
    Besa, N C
    Coldiron, M E
    Bakri, A
    Raji, A
    Nsuami, M J
    Rousseau, C
    Hurtado, N
    Porten, K
    Affiliation
    Epicentre, Paris, France.
    Issue Date
    2013-07-18
    
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    Journal
    Epidemiology and Infection
    Abstract
    SUMMARY A diphtheria outbreak occurred from February to November 2011 in the village of Kimba and its surrounding settlements, in Borno State, northeastern Nigeria. We conducted a retrospective outbreak investigation in Kimba village and the surrounding settlements to better describe the extent and clinical characteristics of this outbreak. Ninety-eight cases met the criteria of the case definition of diphtheria, 63 (64·3%) of whom were children aged <10 years; 98% of cases had never been immunized against diphtheria. None of the 98 cases received diphtheria antitoxin, penicillin, or erythromycin during their illness. The overall case-fatality ratio was 21·4%, and was highest in children aged 0-4 years (42·9%). Low rates of immunization, delayed clinical recognition of diphtheria and absence of treatment with antitoxin and appropriate antibiotics contributed to this epidemic and its severity.
    Publisher
    Cambridge University Press
    URI
    http://hdl.handle.net/10144/303703
    DOI
    10.1017/S0950268813001696
    PubMed ID
    23866913
    Language
    en
    ISSN
    1469-4409
    ae974a485f413a2113503eed53cd6c53
    10.1017/S0950268813001696
    Scopus Count
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