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    Jan 20, 2021
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    Pooled HIV-1 Viral Load Testing Using Dried Blood Spots to Reduce the Cost of Monitoring Antiretroviral Treatment in a Resource-Limited Setting

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    Authors
    Pannus, Pieter
    Fajardo, Emmanuel
    Metcalf, Carol
    Coulborn, Rebecca M
    Durán, Laura T
    Bygrave, Helen
    Ellman, Tom
    Garone, Daniela
    Murowa, Michael
    Mwenda, Reuben
    Reid, Tony
    Preiser, Wolfgang
    Show allShow less
    Affiliation
    *Médecins Sans Frontières, Southern Africa Medical Unit, Cape Town, South Africa; †Médecins Sans Frontières, Thyolo, Malawi; ‡Ministry of Health, Health Technical Support Services, Diagnostics, District Management Office, Thyolo, Malawi; §Ministry of Health, Lilongwe, Malawi; ‖Médecins Sans Frontières, Operational Research Unit, Brussels, Belgium; and ¶Division of Medical Virology, Stellenbosch University, and National Health Laboratory Service, Tygerberg, South Africa.
    Issue Date
    2013-10-01
    
    Metadata
    Show full item record
    Journal
    Journal of Acquired Immune Deficiency Syndromes (1999)
    Abstract
    : Rollout of routine HIV-1 viral load monitoring is hampered by high costs and logistical difficulties associated with sample collection and transport. New strategies are needed to overcome these constraints. Dried blood spots from finger pricks have been shown to be more practical than the use of plasma specimens, and pooling strategies using plasma specimens have been demonstrated to be an efficient method to reduce costs. This study found that combination of finger-prick dried blood spots and a pooling strategy is a feasible and efficient option to reduce costs, while maintaining accuracy in the context of a district hospital in Malawi.
    Publisher
    Lippincott Williams & Wilkins
    URI
    http://hdl.handle.net/10144/305934
    DOI
    10.1097/QAI.0b013e3182a61e63
    PubMed ID
    23892241
    Language
    en
    ISSN
    1944-7884
    ae974a485f413a2113503eed53cd6c53
    10.1097/QAI.0b013e3182a61e63
    Scopus Count
    Collections
    HIV/AIDS

    entitlement

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