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dc.contributor.authorKlarkowski, Derryck
dc.contributor.authorGlass, Kathryn
dc.contributor.authorO'Brien, Daniel
dc.contributor.authorLokuge, Kamalini
dc.contributor.authorPiriou, Erwan
dc.contributor.authorShanks, Leslie
dc.date.accessioned2014-01-20T20:41:49Z
dc.date.available2014-01-20T20:41:49Z
dc.date.issued2013-11
dc.identifier.citationVariation in Specificity of HIV Rapid Diagnostic Tests over Place and Time: An Analysis of Discordancy Data Using a Bayesian Approach. 2013, 8 (11):e81656 PLoS ONEen_GB
dc.identifier.issn1932-6203
dc.identifier.pmid24282615
dc.identifier.doi10.1371/journal.pone.0081656
dc.identifier.urihttp://hdl.handle.net/10144/311607
dc.description.abstractRecent trends to earlier access to anti-retroviral treatment underline the importance of accurate HIV diagnosis. The WHO HIV testing strategy recommends the use of two or three rapid diagnostic tests (RDTs) combined in an algorithm and assume a population is serologically stable over time. Yet RDTs are prone to cross reactivity which can lead to false positive or discordant results. This paper uses discordancy data from Médecins Sans Frontières (MSF) programmes to test the hypothesis that the specificity of RDTs change over place and time.
dc.language.isoenen
dc.publisherPublic Library of Scienceen_GB
dc.rightsPublished by Public Library of Science, [url]http://www.plosone.org/[/url] Archived on this site by Open Access permissionen_GB
dc.subjectDiagnosticsen_GB
dc.subjectHIV/AIDSen_GB
dc.titleVariation in Specificity of HIV Rapid Diagnostic Tests over Place and Time: An Analysis of Discordancy Data Using a Bayesian Approachen
dc.contributor.departmentMédecins sans Frontières, Operational Centre Amsterdam, Amsterdam, The Netherlandsen_GB
dc.identifier.journalPloS ONEen_GB
refterms.dateFOA2019-03-04T10:58:05Z
html.description.abstractRecent trends to earlier access to anti-retroviral treatment underline the importance of accurate HIV diagnosis. The WHO HIV testing strategy recommends the use of two or three rapid diagnostic tests (RDTs) combined in an algorithm and assume a population is serologically stable over time. Yet RDTs are prone to cross reactivity which can lead to false positive or discordant results. This paper uses discordancy data from Médecins Sans Frontières (MSF) programmes to test the hypothesis that the specificity of RDTs change over place and time.


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