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    Jan 26, 2021
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    Five-Year Field Results and Long-Term Effectiveness of 20 mg/kg Liposomal Amphotericin B (Ambisome) for Visceral Leishmaniasis in Bihar, India

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    Burza et al-2014-Five year field ...
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    Authors
    Burza, Sakib
    Sinha, Prabhat K
    Mahajan, Raman
    Lima, María Angeles
    Mitra, Gaurab
    Verma, Neena
    Balasegarem, Manica
    Das, Pradeep
    Issue Date
    2014-01
    
    Metadata
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    Journal
    PLoS Neglected Tropical Diseases
    Abstract
    Visceral Leishmaniasis (VL; also known as Kala-azar) is an ultimately fatal disease endemic in Bihar. A 2007 observational cohort study in Bihar of 251 patients with VL treated with 20 mg/Kg intravenous liposomal amphotericin B (Ambisome) demonstrated a 98% cure rate at 6-months. Between July 2007 and August 2012, Médecins Sans Frontières (MSF) and the Rajendra Memorial Research Institute (RMRI) implemented a VL treatment project in Bihar, India-an area highly endemic for Leishmania donovani-using this regimen as first-line treatment.
    Publisher
    Public Library of Science
    URI
    http://hdl.handle.net/10144/311611
    DOI
    10.1371/journal.pntd.0002603
    PubMed ID
    24392168
    Language
    en
    ISSN
    1935-2735
    ae974a485f413a2113503eed53cd6c53
    10.1371/journal.pntd.0002603
    Scopus Count
    Collections
    Leishmaniasis/Kala Azar

    entitlement

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