• Active Case-Finding for Tuberculosis by Mobile Teams in Myanmar: Yield and Treatment Outcomes

      Myint, O; Saw, S; Isaakidis, P; Khogali, M; Reid, A; Hoa, N; Kyaw, T; Zaw, K; Khaing, T; Aung, S (BioMed Central, 2017-06-02)
      Since 2005, the Myanmar National Tuberculosis Programme (NTP) has been implementing active case finding (ACF) activities involving mobile teams in hard-to-reach areas. This study revealed the contribution of mobile team activities to total tuberculosis (TB) case detection, characteristics of TB patients detected by mobile teams and their treatment outcomes.
    • Alarming prevalence and clustering of Modifiable Noncommunicable Disease risk factors among adults in Bhutan: a nationwide cross-sectional community survey

      Pelzom, D; Isaakidis, P; Oo, MM; Gurung, MS; Yangchen, P (BioMed Central, 2017-12-21)
      Bhutan is currently facing a double burden of non-communicable (NCDs) and communicable diseases, with rising trends of NCDs. The 2014 STEPS survey identified high prevalence of several NCD risk factors; however, associations with socio-demographic characteristics as well as clustering of risk factors were not assessed. This study aimed to determine the distribution and clustering of modifiable NCD risk factors among adults in Bhutan and their demographic and social determinants.
    • Different Challenges, Different Approaches and Related Expenditures of Community-Based Tuberculosis Activities by International Non-Governmental Organizations in Myanmar

      Han, WW; Saw, S; Isaakidis, P; Khogali, M; Reid, A; Hoa, N; Zaw, KK; Aung, ST (BioMed Central, 2017-03-24)
      International non-governmental organizations (INGOs) have been implementing community-based tuberculosis (TB) care (CBTBC) in Myanmar since 2011. Although the National TB Programme (NTP) ultimately plans to take over CBTBC, there have been no evaluations of the models of care or of the costs of providing CBTBC in Myanmar by INGOs.
    • Effect of Previous Utilization and Out-Of-Pocket Expenditure on Subsequent Utilization of a State Led Public-Private Partnership Scheme "Chiranjeevi Yojana" to Promote Facility Births in Gujarat, India

      Yasobant, S; Shewade, HD; Vora, KS; Annerstedt, KS; Isaakidis, P; Dholakia, NB; Mavalankar, DV (BioMed Central, 2017-04-25)
      In Gujarat, India, a state led public private partnership scheme to promote facility birth named Chiranjeevi Yojana (CY) was implemented in 2005. Institutional birth is provided free of cost at accredited private health facilities to women from socially disadvantaged groups (eligible women). CY has contributed in increasing facility birth and providing substantially subsidized (but not totally free) birth care; however, the retention of mothers in this scheme in subsequent child birth is unknown. Therefore, we conducted a study aimed to determine the effect of previous utilization of the scheme and previous out of pocket expenditure on subsequent child birth among multiparous eligible women in Gujarat.
    • Factors associated with death and loss to follow-up in children on antiretroviral care in Mingalardon Specialist Hospital, Myanmar, 2006-2016

      Kaung Nyunt, KK; Han, WW; Satyanarayana, S; Isaakidis, P; Hone, S; Khaing, AA; Nguyen Binh, H; Oo, HN (Public Library of Science, 2018-04-05)
      Myanmar National AIDS programme's priority is to improve the survival of all people living with HIV by providing anti-retroviral therapy (ART) care. More than 7200 children (aged <15 years) have been enrolled into ART care from 2005 to 2016. A previous study showed that ~11% children on ART care had either died or were lost to follow-up by 60 months. Factors associated with death and lost-to follow-up (adverse outcomes) have not been previously studied.
    • Factors Associated with Unfavorable Treatment Outcomes in New and Previously Treated TB Patients in Uzbekistan: A Five Year Countrywide Study

      Gadoev, J; Asadov, D; Tillashaykhov, M; Tayler-Smith, K; Isaakidis, P; Dadu, A; Colombani, P d; Gudmund Hinderaker, S; Parpieva, N; Ulmasova, D; Jalolov, A; Hamraev, A; Ali, E; Boom, M v d; Hammerich, A; Gozalov, O; Dara, M (Public Library of Science, 2015-06-15)
      TB is one of the main health priorities in Uzbekistan and relatively high rates of unfavorable treatment outcomes have recently been reported. This requires closer analysis to explain the reasons and recommend interventions to improve the situation. Thus, by using countrywide data this study sought to determine trends in unfavorable outcomes (lost-to-follow-ups, deaths and treatment failures) and describe their associations with socio-demographic and clinical factors.
    • "I Wasted 3 Years, Thinking It's Not a Problem": Patient and Health System Delays in Diagnosis of Leprosy in India: A Mixed-Methods Study

      Muthuvel, T; Govindarajulu, S; Isaakidis, P; Shewade, HD; Rokade, V; Singh, R; Kamble, S (Public Library of Science, 2017-01-12)
      Worldwide, leprosy is one of the major causes of preventable disability. India contributes to 60% of global leprosy burden. With increasing numbers of leprosy with grade 2 disability (visible disability) at diagnosis, we aimed to determine risk factors associated with grade 2 disability among new cases and explore patients and providers' perspectives into reasons for late presentation.
    • Infective endocarditis in Ethiopian children: a hospital based review of cases in Addis Ababa

      Moges, T; Gedlu, E; Isaakidis, P; Kumar, A; Den, R V; Khogali, M; Mekasha, A; Hinderaker, S G (African Field Epidemiology Network, 2015-01-28)
    • Intensive-Phase Treatment Outcomes among Hospitalized Multidrug-Resistant Tuberculosis Patients: Results from a Nationwide Cohort in Nigeria

      Oladimeji, O; Isaakidis, P; Obasanya, O J; Eltayeb, O; Khogali, M; Van den Bergh, R; Kumar, A M V; Hinderaker, S G; Abdurrahman, S T; Lawson, L; Cuevas, L E (Public Library of Science, 2014-04)
      Nigeria is faced with a high burden of Human Immunodeficiency Virus (HIV) infection and multidrug-resistant tuberculosis (MDR-TB). Treatment outcomes among MDR-TB patients registered across the globe have been poor, partly due to high loss-to-follow-up. To address this challenge, MDR-TB patients in Nigeria are hospitalized during the intensive-phase(IP) of treatment (first 6-8 months) and are provided with a package of care including standardized MDR-TB treatment regimen, antiretroviral therapy (ART) and cotrimoxazole prophylaxis (CPT) for HIV-infected patients, nutritional and psychosocial support. In this study, we report the end-IP treatment outcomes among them.
    • Low Mother-to-Child HIV Transmission Rate But High Loss-to-Follow-Up Among Mothers and Babies in Mandalay, Myanmar; A Cohort Study

      Kyaw, K; Oo, M; Kyaw, N; Phyo, K; Aung, T; Mya, T; Aung, N; Oo, H; Isaakidis, P (Public Library of Science, 2017-09-08)
      Loss-to-follow-up (LTFU) throughout the Prevention of Mother-To-Child Transmission (PMTCT) cascade remains one of the major threats to the success of PMTCT programs. In this study, we aimed to determine the mother-to-child transmission rate in a programmatic setting and to determine factors associated with LTFU among enrolled mothers and unfavorable outcomes among HIV-exposed babies which includes being HIV positive, death and LTFU.
    • Open access for operational research publications from low- and middle-income countries: who pays?

      Zachariah, R; Kumar, A M V; Reid, A J; Van den Bergh, R; Isaakidis, P; Draguez, B; Delaunois, P; Nagaraja, S B; Ramsay, A; Reeder, J C; Denisiuk, O; Ali, E; Khogali, M; Hinderaker, S G; Kosgei, R J; van Griensven, J; Quaglio, G L; Maher, D; Billo, N E; Terry, R F; Harries, A D (International Union Against Tuberculosis and Lung Disease, 2014-09-21)
    • Public Health Action for public health action

      Harries, A D; Bianchi, L; Jensen, P M; Pantages, M; Bissell, K; Kumar, A M V; Hinderaker, S G; Tayler-Smith, K; Van den Bergh, R; van den Boogaard, W; Manzi, M; Isaakidis, P; Reid, A J; Zachariah, R (International Union Against Tuberculosis and Lung Disease, 2014-09-21)
    • Recurrent Tuberculosis and Associated Factors: A Five - Year Countrywide Study in Uzbekistan

      Gadoev, J; Asadov, D; Harries, AD; Parpieva, N; Tayler-Smith, K; Isaakidis, P; Ali, E; Hinderaker, SG; Ogtay, G; Ramsay, A; Jalolov, A; Dara, M (Public Library of Science, 2017-05-04)
      In Uzbekistan, despite stable and relatively high tuberculosis treatment success rates, relatively high rates of recurrent tuberculosis have recently been reported. Recurrent tuberculosis is when a patient who was treated for pulmonary tuberculosis and cured, later develops the disease again. This requires closer analysis to identify possible causes and recommend interventions to improve the situation. Using countrywide data, this study aimed to analyse trends in recurrent tuberculosis cases and describe their associations with socio-demographic and clinical factors.
    • "They Know, They Agree, but They Don't Do"- The Paradox of Tuberculosis Case Notification by Private Practitioners in Alappuzha District, Kerala, India

      Philip, S; Isaakidis, P; Sagili, K D; Meharunnisa, A; Mrithyunjayan, S; Kumar, A M V (Public Library of Science, 2015-04-24)
      Despite being a recognized standard of tuberculosis (TB) care internationally, mandatory TB case notification brings forth challenges from the private sector. Only three TB cases were notified in 2013 by private practitioners compared to 2000 TB cases notified yearly from the public sector in Alappuzha district. The study objective was to explore the knowledge, opinion and barriers regarding TB Notification among private practitioners offering TB services in Alappuzha, Kerala state, India.
    • Utilization of the State Led Public Private Partnership Program "Chiranjeevi Yojana" to Promote Facility Births in Gujarat, India: a Cross Sectional Community Based Study

      Yasobant, S; Vora, K S; Shewade, H D; Annerstedt, K S; Isaakidis, P; Mavalankar, D V; Dholakia, N B; De Costa, A (BioMed Central, 2016-07-15)
      "Chiranjeevi Yojana (CY)", a state-led large-scale demand-side financing scheme (DSF) under public-private partnership to increase institutional delivery, has been implemented across Gujarat state, India since 2005. The scheme aims to provide free institutional childbirth services in accredited private health facilities to women from socially disadvantaged groups (eligible women). These services are paid for by the state to the private facility with the intention of service being free to the user. This community-based study estimates CY uptake among eligible women and explores factors associated with non-utilization of the CY program.