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dc.contributor.authorAlvar, J
dc.contributor.authorBashaye, S
dc.contributor.authorArgaw, D
dc.contributor.authorCruz, I
dc.contributor.authorAparicio, P
dc.contributor.authorKassa, A
dc.contributor.authorOrfanos, G
dc.contributor.authorParreño, F
dc.contributor.authorBabaniyi, O
dc.contributor.authorGudeta, N
dc.contributor.authorCañavate, C
dc.contributor.authorBern, C
dc.date.accessioned2008-07-08T15:24:06Z
dc.date.available2008-07-08T15:24:06Z
dc.date.issued2007-08
dc.identifier.citationKala-azar outbreak in Libo Kemkem, Ethiopia: epidemiologic and parasitologic assessment. 2007, 77 (2):275-82 Am. J. Trop. Med. Hyg.en
dc.identifier.issn0002-9637
dc.identifier.pmid17690399
dc.identifier.urihttp://hdl.handle.net/10144/31334
dc.descriptionThis study as conducted in collaboration with MSF Greece and Spain.
dc.description.abstractIn May 2005, visceral leishmaniasis (VL) was recognized for the first time in Libo Kemkem, Ethiopia. In October 2005, a rapid assessment was conducted using data from 492 patients with VL treated in the district health center and a household survey of 584 residents of four villages. One subdistrict accounted for 71% of early cases, but the incidence and number of affected subdistricts increased progressively throughout 2004-2005. In household-based data, we identified 9 treated VL cases, 12 current untreated cases, and 19 deaths attributable to VL (cumulative incidence, 7%). Thirty percent of participants were leishmanin skin test positive (men, 34%; women, 26%; P = 0.06). VL was more common in men than women (9.7% versus 4.5%, P < 0.05), possibly reflecting male outdoor sleeping habits. Molecular typing in splenic aspirates showed L. infantum (six) and L. donovani (one). Local transmission resulted from multiple introductions, is now well established, and will be difficult to eradicate.
dc.language.isoenen
dc.rightsPublished by: American Society of Tropical Medicine and Hygiene. Archived on this site with the kind permission of the American Society of Tropical Medicine and Hygiene, http://www.astmh.orgen
dc.subject.meshAdolescenten
dc.subject.meshAdulten
dc.subject.meshAgglutination Testsen
dc.subject.meshAnimalsen
dc.subject.meshChilden
dc.subject.meshChild, Preschoolen
dc.subject.meshDNA, Intergenicen
dc.subject.meshDNA, Protozoanen
dc.subject.meshDisease Outbreaksen
dc.subject.meshEthiopiaen
dc.subject.meshFemaleen
dc.subject.meshHumansen
dc.subject.meshIncidenceen
dc.subject.meshInfanten
dc.subject.meshLeishmaniaen
dc.subject.meshLeishmaniasis, Visceralen
dc.subject.meshMaleen
dc.subject.meshMiddle Ageden
dc.subject.meshPolymerase Chain Reactionen
dc.subject.meshQuestionnairesen
dc.subject.meshRural Populationen
dc.subject.meshSkin Testsen
dc.titleKala-azar outbreak in Libo Kemkem, Ethiopia: epidemiologic and parasitologic assessment.en
dc.contributor.departmentDepartment for the Control of Neglected Tropical Diseases (CDS/NTD/IDM), Leishmaniasis Control Program, World Health Organization, 20 Avenue Appia, CH-1211 Geneva, Switzerland. alvarj@who.inten
dc.identifier.journalThe American Journal of Tropical Medicine and Hygieneen
refterms.dateFOA2019-03-04T11:06:34Z
html.description.abstractIn May 2005, visceral leishmaniasis (VL) was recognized for the first time in Libo Kemkem, Ethiopia. In October 2005, a rapid assessment was conducted using data from 492 patients with VL treated in the district health center and a household survey of 584 residents of four villages. One subdistrict accounted for 71% of early cases, but the incidence and number of affected subdistricts increased progressively throughout 2004-2005. In household-based data, we identified 9 treated VL cases, 12 current untreated cases, and 19 deaths attributable to VL (cumulative incidence, 7%). Thirty percent of participants were leishmanin skin test positive (men, 34%; women, 26%; P = 0.06). VL was more common in men than women (9.7% versus 4.5%, P < 0.05), possibly reflecting male outdoor sleeping habits. Molecular typing in splenic aspirates showed L. infantum (six) and L. donovani (one). Local transmission resulted from multiple introductions, is now well established, and will be difficult to eradicate.


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