Rotavirus Surveillance in Urban and Rural Areas of Niger, April 2010–March 2012
Authors
Page, Anne-LaureJusot, Viviane
Mamaty, Abdoul-Aziz
Adamou, Lagare
Kaplon, Jérôme
Pothier, Pierre
Djibo, Ali
Manzo, Mahamane L.
Toure, Brahima
Langendorf, Céline
Collard, Jean-Marc
Grais, RFebecca F.
Issue Date
2014-03
Metadata
Show full item recordJournal
Emerging Infectious DiseasesAbstract
Knowledge of rotavirus epidemiology is necessary to make informed decisions about vaccine introduction and to evaluate vaccine impact. During April 2010–March 2012, rotavirus surveillance was conducted among 9,745 children <5 years of age in 14 hospitals/health centers in Niger, where rotavirus vaccine has not been introduced. Study participants had acute watery diarrhea and moderate to severe dehydration, and 20% of the children were enrolled in a nutrition program. Of the 9,745 children, 30.6% were rotavirus positive. Genotyping of a subset of positive samples showed a variety of genotypes during the first year, although G2P[4] predominated. G12 genotypes, including G12P[8], which has emerged as a predominant strain in western Africa, represented >80% of isolates during the second year. Hospitalization and death rates and severe dehydration among rotavirus case-patients did not differ during the 2 years. The emergence of G12P[8] warrants close attention to the characteristics of associated epidemics and possible prevention measures.Additional Links
http://wwwnc.cdc.gov/eid/article/20/4/13-1328_article.htmLanguage
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To access this article, click on "Additional Links".ISSN
1080-60401080-6059
ae974a485f413a2113503eed53cd6c53
10.3201/eid2004.131328