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    Apr 11, 2021
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    Emergence of Zaire Ebola Virus Disease in Guinea - Preliminary Report

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    Baize et al-2014-Emergence of ...
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    Authors
    Baize, Sylvain
    Pannetier, Delphine
    Oestereich, Lisa
    Rieger, Toni
    Koivogui, Lamine
    Magassouba, N'faly
    Soropogui, Barrè
    Sow, Mamadou Saliou
    Keïta, Sakoba
    De Clerck, Hilde
    Tiffany, Amanda
    Dominguez, Gemma
    Loua, Mathieu
    Traoré, Alexis
    Kolié, Moussa
    Malano, Emmanuel Roland
    Heleze, Emmanuel
    Bocquin, Anne
    Mély, Stephane
    Raoul, Hervé
    Caro, Valérie
    Cadar, Dániel
    Gabriel, Martin
    Pahlmann, Meike
    Tappe, Dennis
    Schmidt-Chanasit, Jonas
    Impouma, Benido
    Diallo, Abdoul Karim
    Formenty, Pierre
    Van Herp, Michel
    Günther, Stephan
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    Issue Date
    2014-04-16
    
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    Journal
    The New England Journal of Medicine
    Abstract
    In March 2014, the World Health Organization was notified of an outbreak of a communicable disease characterized by fever, severe diarrhea, vomiting, and a high fatality rate in Guinea. Virologic investigation identified Zaire ebolavirus (EBOV) as the causative agent. Full-length genome sequencing and phylogenetic analysis showed that EBOV from Guinea forms a separate clade in relationship to the known EBOV strains from the Democratic Republic of Congo and Gabon. Epidemiologic investigation linked the laboratory-confirmed cases with the presumed first fatality of the outbreak in December 2013. This study demonstrates the emergence of a new EBOV strain in Guinea.
    Publisher
    Massachusetts Medical Society
    URI
    http://hdl.handle.net/10144/326084
    DOI
    10.1056/NEJMoa1404505
    PubMed ID
    24738640
    Language
    en
    ISSN
    1533-4406
    ae974a485f413a2113503eed53cd6c53
    10.1056/NEJMoa1404505
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