Emergence of Zaire Ebola Virus Disease in Guinea - Preliminary Report
Authors
Baize, SylvainPannetier, Delphine
Oestereich, Lisa
Rieger, Toni
Koivogui, Lamine
Magassouba, N'faly
Soropogui, Barrè
Sow, Mamadou Saliou
Keïta, Sakoba
De Clerck, Hilde
Tiffany, Amanda
Dominguez, Gemma
Loua, Mathieu
Traoré, Alexis
Kolié, Moussa
Malano, Emmanuel Roland
Heleze, Emmanuel
Bocquin, Anne
Mély, Stephane
Raoul, Hervé
Caro, Valérie
Cadar, Dániel
Gabriel, Martin
Pahlmann, Meike
Tappe, Dennis
Schmidt-Chanasit, Jonas
Impouma, Benido
Diallo, Abdoul Karim
Formenty, Pierre
Van Herp, Michel
Günther, Stephan
Issue Date
2014-04-16
Metadata
Show full item recordAbstract
In March 2014, the World Health Organization was notified of an outbreak of a communicable disease characterized by fever, severe diarrhea, vomiting, and a high fatality rate in Guinea. Virologic investigation identified Zaire ebolavirus (EBOV) as the causative agent. Full-length genome sequencing and phylogenetic analysis showed that EBOV from Guinea forms a separate clade in relationship to the known EBOV strains from the Democratic Republic of Congo and Gabon. Epidemiologic investigation linked the laboratory-confirmed cases with the presumed first fatality of the outbreak in December 2013. This study demonstrates the emergence of a new EBOV strain in Guinea.Publisher
Massachusetts Medical SocietyPubMed ID
24738640Language
enISSN
1533-4406ae974a485f413a2113503eed53cd6c53
10.1056/NEJMoa1404505
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