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    Jan 17, 2021
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    The kynurenine pathway of tryptophan catabolism, CD4+ T-cell recovery, and mortality among HIV-infected Ugandans initiating antiretroviral therapy.

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    Byakwaga H - 2014 - The Kynurenine ...
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    Authors
    Byakwaga, Helen
    Boum, Yap
    Huang, Yong
    Muzoora, Conrad
    Kembabazi, Annet
    Weiser, Sheri D
    Bennett, John
    Cao, Huyen
    Haberer, Jessica E
    Deeks, Steven G
    Bangsberg, David R
    McCune, Joseph M
    Martin, Jeffrey N
    Hunt, Peter W
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    Issue Date
    2014-08-01
    
    Metadata
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    Journal
    The Journal of Infectious Diseases
    Abstract
    Human immunodeficiency virus (HIV) infection-induced indoleamine 2,3-dioxygenase-1 (IDO) expression in activated monocytes and dendritic cells catabolizes tryptophan to kynurenine and other downstream catabolites that inhibit T-cell proliferation and interleukin 17 (IL-17) production. The prognostic significance of this pathway in treated HIV disease is unknown.
    Publisher
    Oxford University Press
    URI
    http://hdl.handle.net/10144/331942
    DOI
    10.1093/infdis/jiu115
    PubMed ID
    24585899
    Type
    Article
    Language
    en
    ISSN
    1537-6613
    ae974a485f413a2113503eed53cd6c53
    10.1093/infdis/jiu115
    Scopus Count
    Collections
    HIV/AIDS

    entitlement

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