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dc.contributor.authorByakwaga, Helen*
dc.contributor.authorBoum, Yap*
dc.contributor.authorHuang, Yong*
dc.contributor.authorMuzoora, Conrad*
dc.contributor.authorKembabazi, Annet*
dc.contributor.authorWeiser, Sheri D*
dc.contributor.authorBennett, John*
dc.contributor.authorCao, Huyen*
dc.contributor.authorHaberer, Jessica E*
dc.contributor.authorDeeks, Steven G*
dc.contributor.authorBangsberg, David R*
dc.contributor.authorMcCune, Joseph M*
dc.contributor.authorMartin, Jeffrey N*
dc.contributor.authorHunt, Peter W*
dc.date.accessioned2014-09-29T14:05:49Z
dc.date.available2014-09-29T14:05:49Z
dc.date.issued2014-08-01
dc.identifier.citationThe kynurenine pathway of tryptophan catabolism, CD4+ T-cell recovery, and mortality among HIV-infected Ugandans initiating antiretroviral therapy. 2014, 210 (3):383-91 J. Infect. Dis.en_GB
dc.identifier.issn1537-6613
dc.identifier.pmid24585899
dc.identifier.doi10.1093/infdis/jiu115
dc.identifier.urihttp://hdl.handle.net/10144/331942
dc.description.abstractHuman immunodeficiency virus (HIV) infection-induced indoleamine 2,3-dioxygenase-1 (IDO) expression in activated monocytes and dendritic cells catabolizes tryptophan to kynurenine and other downstream catabolites that inhibit T-cell proliferation and interleukin 17 (IL-17) production. The prognostic significance of this pathway in treated HIV disease is unknown.
dc.language.isoenen
dc.publisherOxford University Pressen_GB
dc.rightsPublished by Infectious Diseases Society of America Archived on this site with permission and copyright 2014 by the Infectious Diseases Society of America, [url] and Oxford University Pressen_GB
dc.subjectHIVen_GB
dc.subject.meshAdulten_GB
dc.subject.meshAnti-HIV Agentsen_GB
dc.subject.meshCD4 Lymphocyte Counten_GB
dc.subject.meshCD4-Positive T-Lymphocytesen_GB
dc.subject.meshFemaleen_GB
dc.subject.meshHIV Infectionsen_GB
dc.subject.meshHumansen_GB
dc.subject.meshKynurenineen_GB
dc.subject.meshMaleen_GB
dc.subject.meshTryptophanen_GB
dc.subject.meshUgandaen_GB
dc.titleThe kynurenine pathway of tryptophan catabolism, CD4+ T-cell recovery, and mortality among HIV-infected Ugandans initiating antiretroviral therapy.en
dc.typeArticleen
dc.identifier.journalThe Journal of Infectious Diseasesen_GB
refterms.dateFOA2015-01-08T00:00:00Z
html.description.abstractHuman immunodeficiency virus (HIV) infection-induced indoleamine 2,3-dioxygenase-1 (IDO) expression in activated monocytes and dendritic cells catabolizes tryptophan to kynurenine and other downstream catabolites that inhibit T-cell proliferation and interleukin 17 (IL-17) production. The prognostic significance of this pathway in treated HIV disease is unknown.


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