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dc.contributor.authorThurtle, N
dc.contributor.authorGreig, J
dc.contributor.authorCooney, L
dc.contributor.authorAmitai, Y
dc.contributor.authorAriti, C
dc.contributor.authorBrown, M J
dc.contributor.authorKosnett, M J
dc.contributor.authorMoussally, K
dc.contributor.authorSani-Gwarzo, N
dc.contributor.authorAkpan, H
dc.contributor.authorShanks, L
dc.contributor.authorDargan, P I
dc.date.accessioned2014-10-17T15:41:12Z
dc.date.available2014-10-17T15:41:12Z
dc.date.issued2014-10-07
dc.identifier.citationDescription of 3,180 Courses of Chelation with Dimercaptosuccinic Acid in Children ≤5 y with Severe Lead Poisoning in Zamfara, Northern Nigeria: A Retrospective Analysis of Programme Data. 2014, 11 (10):e1001739 PLoS Med.en_GB
dc.identifier.issn1549-1676
dc.identifier.pmid25291378
dc.identifier.doi10.1371/journal.pmed.1001739
dc.identifier.urihttp://hdl.handle.net/10144/332891
dc.description.abstractIn 2010, Médecins Sans Frontières (MSF) discovered extensive lead poisoning impacting several thousand children in rural northern Nigeria. An estimated 400 fatalities had occurred over 3 mo. The US Centers for Disease Control and Prevention (CDC) confirmed widespread contamination from lead-rich ore being processed for gold, and environmental management was begun. MSF commenced a medical management programme that included treatment with the oral chelating agent 2,3-dimercaptosuccinic acid (DMSA, succimer). Here we describe and evaluate the changes in venous blood lead level (VBLL) associated with DMSA treatment in the largest cohort of children ≤5 y of age with severe paediatric lead intoxication reported to date to our knowledge.
dc.language.isoenen
dc.publisherPublic Library of Scienceen_GB
dc.rightsPublished by Public Library of Science, [url]http://medicine.plosjournals.org/[/url] Archived on this site by Open Access permissionen_GB
dc.titleDescription of 3,180 Courses of Chelation with Dimercaptosuccinic Acid in Children ≤5 y with Severe Lead Poisoning in Zamfara, Northern Nigeria: A Retrospective Analysis of Programme Dataen
dc.identifier.journalPLoS Medicineen_GB
refterms.dateFOA2019-03-04T11:30:59Z
html.description.abstractIn 2010, Médecins Sans Frontières (MSF) discovered extensive lead poisoning impacting several thousand children in rural northern Nigeria. An estimated 400 fatalities had occurred over 3 mo. The US Centers for Disease Control and Prevention (CDC) confirmed widespread contamination from lead-rich ore being processed for gold, and environmental management was begun. MSF commenced a medical management programme that included treatment with the oral chelating agent 2,3-dimercaptosuccinic acid (DMSA, succimer). Here we describe and evaluate the changes in venous blood lead level (VBLL) associated with DMSA treatment in the largest cohort of children ≤5 y of age with severe paediatric lead intoxication reported to date to our knowledge.


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