• Login
    View Item 
    •   Home
    • 1 Published Research and Commentary
    • TB
    • View Item
    •   Home
    • 1 Published Research and Commentary
    • TB
    • View Item
    Jan 23, 2021
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of MSFTitleAuthorsSubjectsPublisherJournalThis CollectionTitleAuthorsSubjectsPublisherJournal

    Male Gender is independently associated with pulmonary tuberculosis among sputum and non-sputum producers people with presumptive tuberculosis in Southwestern Uganda

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Thumbnail
    Name:
    Boum et al - 2014 - Male Gender ...
    Size:
    287.7Kb
    Format:
    PDF
    Description:
    Main article
    Download
    Authors
    Boum, Y
    Atwine, D
    Orikiriza, P
    Assimwe, J
    Page, A-L
    Mwanga-Amumpaire, J
    Bonnet, M
    Issue Date
    2014-12-10
    
    Metadata
    Show full item record
    Journal
    BMC Infectious Diseases
    Abstract
    BackgroundLittle is known about the association between gender and risk of TB infection. We sought to assess the impact of gender on TB prevalence among people with presumptive tuberculosis at a regional referral hospital in a high TB and HIV prevalence setting.MethodsWe analyzed data from two diagnostic TB studies conducted in rural, southwestern Uganda. People with presumptive tuberculosis were evaluated by chest X-ray, fluorescence microscopy, TB culture, and HIV testing. Our primary outcome of interest was TB infection, as defined by a positive TB culture. Our primary explanatory variable of interest was gender. We fit univariable and multivariable logistic regression models to investigate associations between TB infection and gender, before and after adjusting or possible confounding factors, including ability to produce sputum, age and residence.ResultsBetween April 2010 and September 2012, 863 people with presumptive tuberculosis (PWPTB) were enrolled in the two studies at Mbarara Regional Referral Hospital (MRRH) in Uganda. Among them 664 (76.9%) were able to produce sputum. X-ray was suggestive of TB for 258 (66.5%) of males and 175 (44.8%) of female (p¿<¿0.001). using microscopy 84 (20%) of males and 48 (10.9%) of females were diagnosed with TB (p¿<¿0.001) while 122 (30.3%) of males and 76 (18.4%) of females were diagnosed with TB (p¿<¿0.001) using TB culture.In multivariable logistic regression models, the odds of having TB was higher in males than females (AOR 2.2 (1.56-3.18 95%CI°, P¿<¿0.001), after adjustment for age, HIV status, ability to produce sputum, and residence.ConclusionIn Southwestern Uganda, TB prevalence is higher among male than female people with presumptive TB. The increased risk of TB among males is independent of other TB risk factors. These findings emphasize the need for gender-focused interventions aimed at reducing TB transmission.
    Publisher
    BioMed Central
    URI
    http://hdl.handle.net/10144/337711
    DOI
    10.1186/s12879-014-0638-5
    PubMed ID
    25492725
    Language
    en
    ISSN
    1471-2334
    ae974a485f413a2113503eed53cd6c53
    10.1186/s12879-014-0638-5
    Scopus Count
    Collections
    TB

    entitlement

    Related articles

    • Performance of loop-mediated isothermal amplification assay in the diagnosis of pulmonary tuberculosis in a high prevalence TB/HIV rural setting in Uganda.
    • Authors: Nakiyingi L, Nakanwagi P, Briggs J, Agaba T, Mubiru F, Mugenyi M, Ssengooba W, Joloba ML, Manabe YC
    • Issue date: 2018 Feb 21
    • Predictors and outcomes of mycobacteremia among HIV-infected smear- negative presumptive tuberculosis patients in Uganda.
    • Authors: Nakiyingi L, Ssengooba W, Nakanjako D, Armstrong D, Holshouser M, Kirenga BJ, Shah M, Mayanja-Kizza H, Joloba ML, Ellner JJ, Dorman SE, Manabe YC
    • Issue date: 2015 Feb 15
    • Prevalence of Tuberculosis Risk Factors among Bacteriologically Negative and Bacteriologically Confirmed Tuberculosis Patients from Five Regional Referral Hospitals in Uganda.
    • Authors: Muttamba W, Kirenga B, Ssengooba W, Sekibira R, Katamba A, Joloba ML
    • Issue date: 2019 Feb
    • Characteristics of sputum smear-positive tuberculosis patients with and without HIV infection in a hospital in Zimbabwe.
    • Authors: Schoch OD, Rieder HL
    • Issue date: 1996 Feb
    • Impact of human immunodeficiency virus type-1 infection on the initial bacteriologic and radiographic manifestations of pulmonary tuberculosis in Uganda. Makerere University-Case Western Reserve University Research Collaboration.
    • Authors: Johnson JL, Vjecha MJ, Okwera A, Hatanga E, Byekwaso F, Wolski K, Aisu T, Whalen CC, Huebner R, Mugerwa RD, Ellner JJ
    • Issue date: 1998 May
    DSpace software (copyright © 2002 - 2021)  DuraSpace
    Quick Guide | Contact Us
    Open Repository is a service operated by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.