Expanding Access to HIV Viral Load Testing: A Systematic Review of RNA Stability in EDTA Tubes and PPT beyond Current Time and Temperature Thresholds
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Bonner K et al - 2014 - Expanding ...
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Authors
Bonner, KimberlySiemieniuk, Reed A
Boozary, Andrew
Roberts, Teri
Fajardo, Emmanuel
Cohn, Jennifer
Issue Date
2014-12-01
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PLoS OneAbstract
HIV viral load (VL) testing is the gold standard for antiretroviral treatment monitoring, but many barriers exist to VL testing in resource-limited settings, including storage and transport limitations for whole blood and plasma. Data from various studies indicate that HIV RNA is stable beyond current recommendations. We conducted a systematic review to assess stability data of HIV RNA in whole blood and plasma across times and temperatures.Publisher
Public Library of SciencePubMed ID
25437009Language
enISSN
1932-6203ae974a485f413a2113503eed53cd6c53
10.1371/journal.pone.0113813