Mycobacterium ulcerans treatment - can antibiotic duration be reduced in selected patients?
Friedman, N Deborah
Hughes, Andrew J
O'Brien, Daniel P
MetadataShow full item record
JournalPLoS Neglected Tropical Diseases
AbstractMycobacterium ulcerans (M. ulcerans) is a necrotizing skin infection endemic to the Bellarine Peninsula, Australia. Current treatment recommendations include 8 weeks of combination antibiotics, with adjuvant surgery if necessary. However, antibiotic toxicity often results in early treatment cessation and local experience suggests that shorter antibiotic courses may be effective with concurrent surgery. We report the outcomes of patients in the Barwon Health M. ulcerans cohort who received shorter courses of antibiotic therapy than 8 weeks.
PublisherPublic Library of Science
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