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Mycobacterium ulcerans treatment - can antibiotic duration be reduced in selected patients?

dc.contributor.authorCowan, Raquel
dc.contributor.authorAthan, Eugene
dc.contributor.authorFriedman, N Deborah
dc.contributor.authorHughes, Andrew J
dc.contributor.authorMcDonald, Anthony
dc.contributor.authorCallan, Peter
dc.contributor.authorFyfe, Janet
dc.contributor.authorO'Brien, Daniel P
dc.date.accessioned2015-03-23T19:09:58Z
dc.date.available2015-03-23T19:09:58Z
dc.date.issued2015-02-06
dc.identifier.citationMycobacterium ulcerans treatment - can antibiotic duration be reduced in selected patients? 2015, 9 (2):e0003503 PLoS Negl Trop Disen_GB
dc.identifier.issn1935-2735
dc.identifier.pmid25658304
dc.identifier.doi10.1371/journal.pntd.0003503
dc.identifier.urihttp://hdl.handle.net/10144/347023
dc.description.abstractMycobacterium ulcerans (M. ulcerans) is a necrotizing skin infection endemic to the Bellarine Peninsula, Australia. Current treatment recommendations include 8 weeks of combination antibiotics, with adjuvant surgery if necessary. However, antibiotic toxicity often results in early treatment cessation and local experience suggests that shorter antibiotic courses may be effective with concurrent surgery. We report the outcomes of patients in the Barwon Health M. ulcerans cohort who received shorter courses of antibiotic therapy than 8 weeks.
dc.language.isoenen
dc.publisherPublic Library of Scienceen_GB
dc.rightsArchived with thanks to PLoS Neglected Tropical Diseasesen_GB
dc.titleMycobacterium ulcerans treatment - can antibiotic duration be reduced in selected patients?en
dc.identifier.journalPLoS Neglected Tropical Diseasesen_GB
refterms.dateFOA2019-03-04T11:52:52Z
html.description.abstractMycobacterium ulcerans (M. ulcerans) is a necrotizing skin infection endemic to the Bellarine Peninsula, Australia. Current treatment recommendations include 8 weeks of combination antibiotics, with adjuvant surgery if necessary. However, antibiotic toxicity often results in early treatment cessation and local experience suggests that shorter antibiotic courses may be effective with concurrent surgery. We report the outcomes of patients in the Barwon Health M. ulcerans cohort who received shorter courses of antibiotic therapy than 8 weeks.


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