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    Apr 18, 2021
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    Substandard medicines in resource-poor settings: A problem that can no longer be ignored

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    Authors
    Caudron, J M
    Ford, N
    Henkens, M
    Macé, C
    Kiddle-Monroe, R
    Pinel, J
    Affiliation
    Médecins Sans Frontières, Geneva, Switzerland; AEDES Foundation, Brussels, Belgium
    Issue Date
    2008-07-08
    Submitted date
    2008-08-28
    
    Metadata
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    Journal
    Tropical Medicine & International Health
    Abstract
    The circulation of substandard medicines in the developing world is a serious clinical and public health concern. Problems include under or over concentration of ingredients, contamination, poor quality ingredients, poor stability and inadequate packaging. There are multiple causes. Drugs manufactured for export are not regulated to the same standard as those for domestic use, while regulatory agencies in the less-developed world are poorly equipped to assess and address the problem. A number of recent initiatives have been established to address the problem, most notably the WHO pre-qualification programme. However, much more action is required. Donors should encourage their partners to include more explicit quality requirements in their tender mechanisms, while purchasers should insist that producers and distributors supply drugs that comply with international quality standards. Governments in rich countries should not tolerate the export of substandard pharmaceutical products to poor countries, while developing country governments should improve their ability to detect substandard medicines.
    URI
    http://hdl.handle.net/10144/37334
    DOI
    10.1111/j.1365-3156.2008.02106.x
    PubMed ID
    18631318
    Additional Links
    http://www3.interscience.wiley.com/journal/120747094/abstract
    Type
    Article
    Language
    en
    ISSN
    1365-3156
    ae974a485f413a2113503eed53cd6c53
    10.1111/j.1365-3156.2008.02106.x
    Scopus Count
    Collections
    Pharmacy

    entitlement

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