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dc.contributor.authorGuthmann, J P
dc.contributor.authorHall, A J
dc.contributor.authorJaffar, S
dc.contributor.authorPalacios, A
dc.contributor.authorLines, J
dc.contributor.authorLlanos-Cuentas, A
dc.date.accessioned2008-09-08T09:18:51Z
dc.date.available2008-09-08T09:18:51Z
dc.date.issued2001
dc.identifier.citationEnvironmental risk factors for clinical malaria: a case-control study in the Grau region of Peru., 95 (6):577-83 Trans. R. Soc. Trop. Med. Hyg.en
dc.identifier.issn0035-9203
dc.identifier.pmid11816424
dc.identifier.urihttp://hdl.handle.net/10144/37452
dc.description.abstractThe role of environmental risk factors in clinical malaria has been studied mainly in Africa and Asia, few investigations have been carried out in Latin America. Field observations in northern coastal Peru, where the prevalence of malaria is high during the agricultural season, suggested that the risk of disease varied according to the characteristics of the house and the house environment. Environmental determinants of the risk of clinical malaria were therefore investigated through a case-control study: 323 clinical cases of malaria, recruited through community-based active case-finding, and 969 age-, sex- and village-matched controls were recruited into the study over a period of 12 months ending June 1997. Residual spraying of houses in the previous 6 months, living more than 100 m from a canal, a level of education equal to primary school or above and working in agriculture conferred significant protection from the risk of developing clinical malaria. The presence of spaces between the wall and roof in the subject's bedroom (eaves) and a house aged > 4 years statistically significantly increased the risk of disease. Based on these results we discuss possible control measures for malaria in this area of the country.
dc.language.isoenen
dc.rightsPublished by Elsevier. Archived on this site with the kind permission of Elsevier Ltd. ([url]http://www.sciencedirect.com/science/journal/00359203[/url]) and the Royal Society of Tropical Medicine and Hygiene ([url]http://www.rstmh.org/transactions.asp[/url])en
dc.subject.meshAdolescenten
dc.subject.meshCase-Control Studiesen
dc.subject.meshChilden
dc.subject.meshChild, Preschoolen
dc.subject.meshCrowdingen
dc.subject.meshEnvironmental Exposureen
dc.subject.meshEnvironmental Healthen
dc.subject.meshFemaleen
dc.subject.meshHousingen
dc.subject.meshHumansen
dc.subject.meshInfanten
dc.subject.meshInfant, Newbornen
dc.subject.meshMalaria, Falciparumen
dc.subject.meshMalaria, Vivaxen
dc.subject.meshMaleen
dc.subject.meshMosquito Controlen
dc.subject.meshMultivariate Analysisen
dc.subject.meshPeruen
dc.subject.meshRisk Factorsen
dc.subject.meshRisk-Takingen
dc.subject.meshSocioeconomic Factorsen
dc.titleEnvironmental risk factors for clinical malaria: a case-control study in the Grau region of Peru.en
dc.contributor.departmentDepartment of Infectious and Tropical Disease, Infectious Disease Epidemiology Unit, London School of Hygiene and Tropical Medicine, UK. jguthmann@epicentre.msf.orgen
dc.identifier.journalTransactions of the Royal Society of Tropical Medicine and Hygieneen
refterms.dateFOA2019-03-04T11:59:55Z
html.description.abstractThe role of environmental risk factors in clinical malaria has been studied mainly in Africa and Asia, few investigations have been carried out in Latin America. Field observations in northern coastal Peru, where the prevalence of malaria is high during the agricultural season, suggested that the risk of disease varied according to the characteristics of the house and the house environment. Environmental determinants of the risk of clinical malaria were therefore investigated through a case-control study: 323 clinical cases of malaria, recruited through community-based active case-finding, and 969 age-, sex- and village-matched controls were recruited into the study over a period of 12 months ending June 1997. Residual spraying of houses in the previous 6 months, living more than 100 m from a canal, a level of education equal to primary school or above and working in agriculture conferred significant protection from the risk of developing clinical malaria. The presence of spaces between the wall and roof in the subject's bedroom (eaves) and a house aged > 4 years statistically significantly increased the risk of disease. Based on these results we discuss possible control measures for malaria in this area of the country.


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