Tuberculosis treatment in complex emergencies: are risks outweighing benefits?
MetadataShow full item record
AbstractTuberculosis (TB) is a major public health problem in complex emergencies. Humanitarian agencies usually postpone the decision to offer TB treatment and opportunities to treat TB patients are often missed. This paper looks at the problem of tuberculosis treatment in these emergencies and questions whether treatment guidelines could be more flexible than international recommendations. A mathematical model is used to calculate the risks and benefits of different treatment scenarios with increasing default rates. Model outcomes are compared to a situation without treatment. An economic analysis further discusses the findings in a trade-off between the extra costs of treating relapses and failures and the savings in future treatment costs. In complex emergencies, if a TB programme could offer 4-month treatment for 75% of its patients, it could still be considered beneficial in terms of public health. In addition, the proportion of patients following at least 4 months of treatment can be used as an indicator to help evaluate the public health harm and benefit of the TB programme.
- The cost of tuberculosis to patients in Sierra Leone's war zone.
- Authors: Gibson N, Boillot F, Jalloh H
- Issue date: 1998 Sep
- [Development of antituberculous drugs: current status and future prospects].
- Authors: Tomioka H, Namba K
- Issue date: 2006 Dec
- Decentralisation of treatment for patients with tuberculosis in Malawi: moving from research to policy and practice.
- Authors: Salaniponi FM, Gausi F, Mphasa N, Nyirenda TE, Kwanjana JH, Harries AD
- Issue date: 2003 Sep
- Factors associated with tuberculosis treatment default among HIV-infected tuberculosis patients in Thailand.
- Authors: Kittikraisak W, Burapat C, Kaewsa-ard S, Watthanaamornkiet W, Sirinak C, Sattayawuthipong W, Jittimanee S, Pobkeeree V, Varma JK
- Issue date: 2009 Jan
- Mortality and failure among tuberculosis patients who did not complete treatment in Vietnam: a cohort study.
- Authors: Vree M, Huong NT, Duong BD, Sy DN, Van le N, Co NV, Cobelens FG, Borgdorff MW
- Issue date: 2007 Jul 2