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    Jan 17, 2021
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    Rapid culture-based methods for drug-resistance detection in Mycobacterium tuberculosis.

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    Authors
    Palomino, J C
    Martin, A
    Von Groll, A
    Portaels, F
    Affiliation
    Mycobacteriology Unit, Institute of Tropical Medicine, Nationalestraat 155, 2000 Antwerp, Belgium.
    Issue Date
    2008-10
    
    Metadata
    Show full item record
    Journal
    Journal of Microbiological Methods
    Abstract
    Tuberculosis still represents a major public health problem, especially in low-resource countries where the burden of the disease is more important. Multidrug-resistant and extensively drug drug-resistant tuberculosis constitute serious problems for the efficient control of the disease stressing the need to investigate resistance to first- and second-line drugs. Conventional methods for detecting drug-resistance in Mycobacterium tuberculosis are slow and cumbersome. The most commonly used proportion method on Löwenstein-Jensen medium or Middlebrook agar requires a minimum of 3-4 weeks to produce results. Several new approaches have been proposed in the last years for the rapid and timely detection of drug-resistance in tuberculosis. This review will address phenotypic culture-based methods for rapid drug susceptibility testing in M. tuberculosis.
    Publisher
    Elsevier
    URI
    http://hdl.handle.net/10144/39615
    DOI
    10.1016/j.mimet.2008.06.015
    PubMed ID
    18627779
    Additional Links
    http://www.sciencedirect.com/science/journal/01677012.
    Language
    en
    ISSN
    0167-7012
    ae974a485f413a2113503eed53cd6c53
    10.1016/j.mimet.2008.06.015
    Scopus Count
    Collections
    TB

    entitlement

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