• Login
    View Item 
    •   Home
    • 1 Published Research and Commentary
    • HIV/AIDS
    • View Item
    •   Home
    • 1 Published Research and Commentary
    • HIV/AIDS
    • View Item
    Mar 04, 2021
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of MSFTitleAuthorsSubjectsPublisherJournalThis CollectionTitleAuthorsSubjectsPublisherJournal

    Providing HIV care for co-infected tuberculosis patients: a perspective from sub-Saharan Africa.

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Thumbnail
    Name:
    Harries Prov HIV care sub-saharan ...
    Size:
    321.1Kb
    Format:
    PDF
    Download
    Authors
    Harries, A D
    Zachariah, R
    Lawn, S D
    Affiliation
    International Union Against Tuberculosis and Lung Disease, Paris, France; Department of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, UK.
    Issue Date
    2009-01
    
    Metadata
    Show full item record
    Journal
    International Journal of Tuberculosis and Lung Disease
    Abstract
    Human immunodeficiency virus/acquired immune-deficiency syndrome (HIV/AIDS) and tuberculosis (TB) are overlapping epidemics that cause an immense burden of disease in sub-Saharan Africa. This region is home to the majority of the world's co-infected patents, who have higher TB case fatality and recurrence rates than patients with TB alone. A World Health Organization interim policy has been developed to reduce the joint burden of TB-HIV disease, an important component of which is provision of HIV care to co-infected patients. This review focuses on HIV testing of TB patients and, for those who are HIV-positive, the administration of adjunctive cotrimoxazole preventive treatment (CPT) and antiretroviral treatment (ART). HIV testing has moved from a voluntary, client-initiated intervention to one that is provider-initiated and a routine part of the diagnostic work-up. The efficacy and safety of CPT in HIV-infected patients is now well established, and this is an essential part of the package of HIV care. ART scale-up in Africa can substantially improve outcomes in co-infected patients. However, the clinical and programmatic challenges of combining ART with anti-tuberculosis treatment need to be resolved to realise the full potential of this benefit. These include the optimal time to start ART, how best to combine rifampicin-containing regimens with first-line and second-line ART regimens, management of immune reconstitution disease, the role of isoniazid preventive treatment with ART after TB treatment completion, and where and how to provide combined treatment to best suit the patient. Clinical and operational studies in the next few years should help to resolve some of these issues.
    URI
    http://hdl.handle.net/10144/48804
    PubMed ID
    19105873
    Language
    en
    ISSN
    1027-3719
    Collections
    TB
    HIV/AIDS

    entitlement

    Related articles

    • Providing HIV care for tuberculosis patients in sub-Saharan Africa.
    • Authors: Harries AD, Boxshall M, Phiri S, van Gorkom J, Zachariah R, Squire SB, Makombe SD, Kwanjana J, Gondwett M
    • Issue date: 2006 Dec
    • Design of regimens for treating tuberculosis in patients with HIV infection, with particular reference to sub-Saharan Africa.
    • Authors: Harries AD, Hargreaves NJ, Salaniponi FM
    • Issue date: 2001 Dec
    • A clinical and epidemiologic update on the interaction between tuberculosis and human immunodeficiency virus infection in adults.
    • Authors: Habib AG
    • Issue date: 2009 Jul-Sep
    • Burden of tuberculosis in an antiretroviral treatment programme in sub-Saharan Africa: impact on treatment outcomes and implications for tuberculosis control.
    • Authors: Lawn SD, Myer L, Bekker LG, Wood R
    • Issue date: 2006 Aug 1
    • Management of adults living with HIV/AIDS in low-income, high-burden settings, with special reference to persons with tuberculosis.
    • Authors: Fujiwara PI, Clevenbergh P, Dlodlo RA
    • Issue date: 2005 Sep
    DSpace software (copyright © 2002 - 2021)  DuraSpace
    Quick Guide | Contact Us
    Open Repository is a service operated by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.