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    Apr 11, 2021
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    Selection of Plasmodium Falciparum pfcrt and pfmdr1 Polymorphisms After Treatment with Artesunate-Amodiaquine Fixed Dose Combination or Artemether-Lumefantrine in Liberia

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    Otienoburu et al - 2016 - Selection ...
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    Authors
    Otienoburu, SD
    Maïga-Ascofaré, O
    Schramm, B
    Jullien, V
    Jones, JJ
    Zolia, YM
    Houzé, P
    Ashley, EA
    Kiechel, JR
    Guérin, PJ
    Le Bras, J
    Houzé, S
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    Issue Date
    2016-09-05
    Submitted date
    2016-09-12
    
    Metadata
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    Journal
    Malaria Journal
    Abstract
    Plasmodium falciparum uncomplicated malaria can successfully be treated with an artemisinin-based combination therapy (ACT). However resistance is spreading to the different ACT compounds; the artemisinin derivative and the partner drug. Studies of P. falciparum polymorphisms associated with drug resistance can provide a useful tool to track resistance and guide treatment policy as well as an in-depth understanding of the development and spread of resistance.
    Publisher
    BioMed Central (Springer Science)
    URI
    http://hdl.handle.net/10144/618654
    DOI
    10.1186/s12936-016-1503-3
    PubMed ID
    27596849
    Language
    en
    ISSN
    1475-2875
    ae974a485f413a2113503eed53cd6c53
    10.1186/s12936-016-1503-3
    Scopus Count
    Collections
    Malaria

    entitlement

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