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    Jan 26, 2021
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    Efficacy of Artemether-Lumefantrine in Relation to Drug Exposure in Children With and Without Severe Acute Malnutrition: an Open Comparative Intervention Study in Mali and Niger

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    Denoeud-Ndam et al - 2016 - ...
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    Authors
    Denoeud-Ndam, L
    Dicko, A
    Baudin, E
    Guindo, O
    Grandesso, F
    Diawara, H
    Sissoko, S
    Sanogo, K
    Traoré, S
    Keita, S
    Barry, A
    de Smet, M
    Lasry, E
    Smit, M
    Wiesner, L
    Barnes, KI
    Djimde, AA
    Guerin, PJ
    Grais, RF
    Doumbo, OK
    Etard, JF
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    Issue Date
    2016-10-24
    Submitted date
    2016-10-31
    
    Metadata
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    Journal
    BMC Medicine
    Abstract
    Severe acute malnutrition (SAM) affects almost all organs and has been associated with reduced intestinal absorption of medicines. However, very limited information is available on the pharmacokinetic properties of antimalarial drugs in this vulnerable population. We assessed artemether-lumefantrine (AL) clinical efficacy in children with SAM compared to those without.
    Publisher
    BioMed Central
    URI
    http://hdl.handle.net/10144/618690
    DOI
    10.1186/s12916-016-0716-1
    PubMed ID
    27776521
    Language
    en
    ISSN
    1741-7015
    ae974a485f413a2113503eed53cd6c53
    10.1186/s12916-016-0716-1
    Scopus Count
    Collections
    Malaria

    entitlement

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