Effectiveness of One Dose of Oral Cholera Vaccine in Response to an Outbreak: A Case-Cohort Study
Authors
Azman, ASParker, LA
Rumunu, J
Tadesse, F
Grandesso, F
Deng, LL
Lino, RL
Bior, BK
Lasuba, M
Page, AL
Ontweka, L
Llosa, AE
Cohuet, S
Pezzoli, L
Sodjinou, DV
Abubakar, A
Debes, AK
Mpairwe, AM
Wamala, JF
Jamet, C
Lessler, J
Sack, DA
Quilici, ML
Ciglenecki, I
Luquero, FJ
Issue Date
2016-11-01
Metadata
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The Lancet. Global healthAbstract
Oral cholera vaccines represent a new effective tool to fight cholera and are licensed as two-dose regimens with 2-4 weeks between doses. Evidence from previous studies suggests that a single dose of oral cholera vaccine might provide substantial direct protection against cholera. During a cholera outbreak in May, 2015, in Juba, South Sudan, the Ministry of Health, Médecins Sans Frontières, and partners engaged in the first field deployment of a single dose of oral cholera vaccine to enhance the outbreak response. We did a vaccine effectiveness study in conjunction with this large public health intervention.Publisher
ElsevierPubMed ID
27765293Language
enISSN
2214-109Xae974a485f413a2113503eed53cd6c53
10.1016/S2214-109X(16)30211-X
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