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dc.contributor.authorLiu, X
dc.contributor.authorSperanza, E
dc.contributor.authorMuñoz-Fontela, C
dc.contributor.authorHaldenby, S
dc.contributor.authorRickett, NY
dc.contributor.authorGarcia-Dorival, I
dc.contributor.authorFang, Y
dc.contributor.authorHall, Y
dc.contributor.authorZekeng, EG
dc.contributor.authorLüdtke, A
dc.contributor.authorXia, D
dc.contributor.authorKerber, R
dc.contributor.authorKrumkamp, R
dc.contributor.authorDuraffour, S
dc.contributor.authorSissoko, D
dc.contributor.authorKenny, J
dc.contributor.authorRockliffe, N
dc.contributor.authorWilliamson, ED
dc.contributor.authorLaws, TR
dc.contributor.authorN'Faly, M
dc.contributor.authorMatthews, DA
dc.contributor.authorGünther, S
dc.contributor.authorCossins, AR
dc.contributor.authorSprecher, A
dc.contributor.authorConnor, JH
dc.contributor.authorCarroll, MW
dc.contributor.authorHiscox, JA
dc.date.accessioned2017-01-25T15:55:38Z
dc.date.available2017-01-25T15:55:38Z
dc.date.issued2017-01-19
dc.date.submitted2017-01-25
dc.identifier.citationTranscriptomic Signatures Differentiate Survival from Fatal Outcomes in Humans Infected with Ebola Virus. 2017, 18 (1):4 Genome Biol.en
dc.identifier.issn1474-760X
dc.identifier.pmid28100256
dc.identifier.doi10.1186/s13059-016-1137-3
dc.identifier.urihttp://hdl.handle.net/10144/618767
dc.description.abstractIn 2014, Western Africa experienced an unanticipated explosion of Ebola virus infections. What distinguishes fatal from non-fatal outcomes remains largely unknown, yet is key to optimising personalised treatment strategies. We used transcriptome data for peripheral blood taken from infected and convalescent recovering patients to identify early stage host factors that are associated with acute illness and those that differentiate patient survival from fatality.
dc.language.isoenen
dc.publisherBioMed Centralen
dc.rightsArchived with thanks to Genome Biologyen
dc.titleTranscriptomic Signatures Differentiate Survival from Fatal Outcomes in Humans Infected with Ebola Virusen
dc.identifier.journalGenome Biologyen
refterms.dateFOA2019-03-04T13:06:06Z
html.description.abstractIn 2014, Western Africa experienced an unanticipated explosion of Ebola virus infections. What distinguishes fatal from non-fatal outcomes remains largely unknown, yet is key to optimising personalised treatment strategies. We used transcriptome data for peripheral blood taken from infected and convalescent recovering patients to identify early stage host factors that are associated with acute illness and those that differentiate patient survival from fatality.


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