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dc.contributor.authorMénard, D
dc.contributor.authorKhim, N
dc.contributor.authorBeghain, J
dc.contributor.authorAdegnika, AA
dc.contributor.authorShafiul-Alam, M
dc.contributor.authorAmodu, O
dc.contributor.authorRahim-Awab, G
dc.contributor.authorBarnadas, C
dc.contributor.authorBerry, A
dc.contributor.authorBoum, Y
dc.contributor.authorBustos, MD
dc.contributor.authorCao, J
dc.contributor.authorChen, JH
dc.contributor.authorCollet, L
dc.contributor.authorCui, L
dc.contributor.authorThakur, GD
dc.contributor.authorDieye, A
dc.contributor.authorDjallé, D
dc.contributor.authorDorkenoo, MA
dc.contributor.authorEboumbou-Moukoko, CE
dc.contributor.authorEspino, FEJ
dc.contributor.authorFandeur, T
dc.contributor.authorFerreira-da-Cruz, MF
dc.contributor.authorFola, AA
dc.contributor.authorFuehrer, HP
dc.contributor.authorHassan, AM
dc.contributor.authorHerrera, S
dc.contributor.authorHongvanthong, B
dc.contributor.authorHouzé, S
dc.contributor.authorIbrahim, ML
dc.contributor.authorJahirul-Karim, M
dc.contributor.authorJiang, L
dc.contributor.authorKano, S
dc.contributor.authorAli-Khan, W
dc.contributor.authorKhanthavong, M
dc.contributor.authorKremsner, PG
dc.contributor.authorLacerda, M
dc.contributor.authorLeang, R
dc.contributor.authorLeelawong, M
dc.contributor.authorLi, M
dc.contributor.authorLin, K
dc.contributor.authorMazarati, JB
dc.contributor.authorMénard, S
dc.contributor.authorMorlais, I
dc.contributor.authorMuhindo-Mavoko, H
dc.contributor.authorMusset, L
dc.contributor.authorNa-Bangchang, K
dc.contributor.authorNambozi, M
dc.contributor.authorNiaré, K
dc.contributor.authorNoedl, H
dc.contributor.authorOuédraogo, JB
dc.contributor.authorPillai, DR
dc.contributor.authorPradines, B
dc.contributor.authorQuang-Phuc, B
dc.contributor.authorRamharter, M
dc.contributor.authorRandrianarivelojosia, M
dc.contributor.authorSattabongkot, J
dc.contributor.authorSheikh-Omar, A
dc.contributor.authorSilué, KD
dc.contributor.authorSirima, SB
dc.contributor.authorSutherland, C
dc.contributor.authorSyafruddin, D
dc.contributor.authorTahar, R
dc.contributor.authorTang, LH
dc.contributor.authorTouré, OA
dc.contributor.authorTshibangu-wa-Tshibangu, P
dc.contributor.authorVigan-Womas, I
dc.contributor.authorWarsame, M
dc.contributor.authorWini, L
dc.contributor.authorZakeri, S
dc.contributor.authorKim, S
dc.contributor.authorEam, R
dc.contributor.authorBerne, L
dc.contributor.authorKhean, C
dc.contributor.authorChy, S
dc.contributor.authorKen, M
dc.contributor.authorLoch, K
dc.contributor.authorCanier, L
dc.contributor.authorDuru, V
dc.contributor.authorLegrand, E
dc.contributor.authorBarale, JC
dc.contributor.authorStokes, B
dc.contributor.authorStraimer, J
dc.contributor.authorWitkowski, B
dc.contributor.authorFidock, DA
dc.contributor.authorRogier, C
dc.contributor.authorRingwald, P
dc.contributor.authorAriey, F
dc.contributor.authorMercereau-Puijalon, O
dc.date.accessioned2017-01-25T16:24:51Z
dc.date.available2017-01-25T16:24:51Z
dc.date.issued2016-06-23
dc.date.submitted2017-01-19
dc.identifier.citationA Worldwide Map of Plasmodium Falciparum K13-Propeller Polymorphisms. 2016, 374 (25):2453-64 N. Engl. J. Med.en
dc.identifier.issn1533-4406
dc.identifier.pmid27332904
dc.identifier.doi10.1056/NEJMoa1513137
dc.identifier.urihttp://hdl.handle.net/10144/618776
dc.description.abstractRecent gains in reducing the global burden of malaria are threatened by the emergence of Plasmodium falciparum resistance to artemisinins. The discovery that mutations in portions of a P. falciparum gene encoding kelch (K13)-propeller domains are the major determinant of resistance has provided opportunities for monitoring such resistance on a global scale.
dc.language.isoenen
dc.publisherMassachusetts Medical Societyen
dc.rightsArchived with thanks to The New England Journal of Medicineen
dc.subject.meshAlgorithmsen
dc.subject.meshArtemisininsen
dc.subject.meshAsia, Southeasternen
dc.subject.meshChinaen
dc.subject.meshDrug Resistanceen
dc.subject.meshEndemic Diseasesen
dc.subject.meshGenotypeen
dc.subject.meshHumansen
dc.subject.meshLactonesen
dc.subject.meshMalaria, Falciparumen
dc.subject.meshMutationen
dc.subject.meshPlasmodium falciparumen
dc.subject.meshPolymorphism, Geneticen
dc.subject.meshProtozoan Proteinsen
dc.subject.meshSequence Analysis, DNAen
dc.titleA Worldwide Map of Plasmodium Falciparum K13-Propeller Polymorphismsen
dc.identifier.journalThe New England Journal of Medicineen
refterms.dateFOA2019-03-04T13:07:00Z
html.description.abstractRecent gains in reducing the global burden of malaria are threatened by the emergence of Plasmodium falciparum resistance to artemisinins. The discovery that mutations in portions of a P. falciparum gene encoding kelch (K13)-propeller domains are the major determinant of resistance has provided opportunities for monitoring such resistance on a global scale.


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