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    Jan 15, 2021
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    First Newborn Baby to Receive Experimental Therapies Survives Ebola Virus Disease

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    Dornermann J et al - 2017 - First ...
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    Authors
    Dörnemann, J
    Burzio, C
    Ronsse, A
    Sprecher, A
    De Clerck, H
    Van Herp, M
    Kolié, MC
    Yosifiva, V
    Caluwaerts, S
    McElroy, AK
    Antierens, A
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    Issue Date
    2017-01-09
    Submitted date
    2017-01-18
    
    Metadata
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    Journal
    The Journal of Infectious Diseases
    Abstract
    A neonate born to an Ebola virus-positive woman was diagnosed with Ebola virus infection on her first day of life. The patient was treated with monoclonal antibodies (ZMapp), a buffy coat transfusion from an Ebola survivor, and the broad-spectrum antiviral GS-5734. On day 20, a venous blood specimen tested negative for Ebola virus by quantitative reverse-transcription polymerase chain reaction. The patient was discharged in good health on day 33 of life. Further follow-up consultations showed age-appropriate weight gain and neurodevelopment at the age of 12 months. This patient is the first neonate documented to have survived congenital infection with Ebola virus.
    Publisher
    Oxford University Press
    URI
    http://hdl.handle.net/10144/618787
    DOI
    10.1093/infdis/jiw493
    PubMed ID
    28073857
    Language
    en
    ISSN
    1537-6613
    ae974a485f413a2113503eed53cd6c53
    10.1093/infdis/jiw493
    Scopus Count
    Collections
    Paediatrics

    entitlement

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