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    Jan 17, 2021
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    Ebola Virus Disease: An Update On Current Prevention and Management Strategies

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    Name:
    Trad MA et al - 2016 - Ebola ...
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    Authors
    Trad, MA
    Naughton, W
    Yeung, A
    Mazlin, L
    O'sullivan, M
    Gilroy, N
    Fisher, DA
    Stuart, RL
    Issue Date
    2016-11-11
    Submitted date
    2016-12-05
    
    Metadata
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    Journal
    Journal of Clinical Virology: The Official Publication of the Pan American Society for Clinical Virology
    Abstract
    Ebola virus disease (EVD) is characterised by systemic viral replication, immuno-suppression, abnormal inflammatory responses, large volume fluid and electrolyte losses, and high mortality in under-resourced settings. There are various therapeutic strategies targeting EVD including vaccines utilizing different antigen delivery methods, antibody-based therapies and antiviral drugs. These therapies remain experimental, but received attention following their use particularly in cases treated outside West Africa during the 2014-15 outbreak, in which 20 (80%) out of 25 patients survived. Emerging data from current trials look promising and are undergoing further study, however optimised supportive care remains the key to reducing mortality from EVD.
    Publisher
    Elsevier
    URI
    http://hdl.handle.net/10144/618818
    DOI
    10.1016/j.jcv.2016.11.005
    PubMed ID
    27893999
    Language
    en
    ISSN
    1873-5967
    ae974a485f413a2113503eed53cd6c53
    10.1016/j.jcv.2016.11.005
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