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    Mar 03, 2021
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    Using Simulation to Aid Trial Design: Ring-Vaccination Trials.

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    Name:
    Hitchings MT et al - 2017 - Using ...
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    Authors
    Hitchings, MD
    Grais, RFF
    Lipsitch, M
    Issue Date
    2017-03-22
    Submitted date
    2017-03-29
    
    Metadata
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    Journal
    PLoS Neglected Tropical Diseases
    Abstract
    The 2014-6 West African Ebola epidemic highlights the need for rigorous, rapid clinical trial methods for vaccines. A challenge for trial design is making sample size calculations based on incidence within the trial, total vaccine effect, and intracluster correlation, when these parameters are uncertain in the presence of indirect effects of vaccination.
    Publisher
    Public Library of Science
    URI
    http://hdl.handle.net/10144/618875
    DOI
    10.1371/journal.pntd.0005470
    PubMed ID
    28328984
    Language
    en
    ISSN
    1935-2735
    ae974a485f413a2113503eed53cd6c53
    10.1371/journal.pntd.0005470
    Scopus Count
    Collections
    Vaccination

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