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    Jan 16, 2021
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    Scale-up of Routine Viral Load Testing in Resource-Poor Settings: Current and Future Implementation Challenges

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    Roberts T et al - 2016 - Scale-up ...
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    Authors
    Roberts, T
    Cohn, J
    Bonner, K
    Hargreaves, S
    Issue Date
    2016-04-15
    
    Metadata
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    Journal
    Clinical Infectious Diseases : an official publication of the Infectious Diseases Society of America
    Abstract
    Despite immense progress in antiretroviral therapy (ART) scale-up, many people still lack access to basic standards of care, with our ability to meet the Joint United Nations Programme on HIV/AIDS 90-90-90 treatment targets for HIV/AIDS dependent on dramatic improvements in diagnostics. The World Health Organization recommends routine monitoring of ART effectiveness using viral load (VL) testing at 6 months and every 12 months, to monitor treatment adherence and minimize failure, and will publish its VL toolkit later this year. However, the cost and complexity of VL is preventing scale-up beyond developed countries and there is a lack of awareness among clinicians as to the long-term patient benefits and its role in prolonging the longevity of treatment programs. With developments in this diagnostic field rapidly evolving-including the recent improvements for accurately using dried blood spots and the imminent appearance to the market of point-of-care technologies offering decentralized diagnosis-we describe current barriers to VL testing in resource-limited settings. Effective scale-up can be achieved through health system and laboratory system strengthening and test price reductions, as well as tackling multiple programmatic and funding challenges.
    Publisher
    Oxford University Press
    URI
    http://hdl.handle.net/10144/618888
    DOI
    10.1093/cid/ciw001
    PubMed ID
    26743094
    Language
    en
    ISSN
    1537-6591
    ae974a485f413a2113503eed53cd6c53
    10.1093/cid/ciw001
    Scopus Count
    Collections
    HIV/AIDS

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