• Login
    View Item 
    •   Home
    • 1 Published Research and Commentary
    • Other Diseases
    • View Item
    •   Home
    • 1 Published Research and Commentary
    • Other Diseases
    • View Item
    Jan 19, 2021
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of MSFTitleAuthorsSubjectsPublisherJournalThis CollectionTitleAuthorsSubjectsPublisherJournal

    The Impact of Control Strategies and Behavioural Changes on the Elimination of Ebola from Lofa County, Liberia

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Thumbnail
    Name:
    20160302.full.pdf
    Size:
    846.1Kb
    Format:
    PDF
    Download
    Authors
    Funk, S
    Ciglenecki, I
    Tiffany, A
    Gignoux, E
    Camacho, A
    Eggo, RM
    Kucharski, AJ
    Edmunds, WJ
    Bolongei, J
    Azuma, P
    Clement, P
    Alpha, TS
    Sterk, E
    Telfer, B
    Engel, G
    Parker, LA
    Suzuki, M
    Heijenberg, N
    Reeder, B
    Show allShow less
    Issue Date
    2017-05-26
    Submitted date
    2017-04-17
    
    Metadata
    Show full item record
    Journal
    Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
    Abstract
    The Ebola epidemic in West Africa was stopped by an enormous concerted effort of local communities and national and international organizations. It is not clear, however, how much the public health response and behavioural changes in affected communities, respectively, contributed to ending the outbreak. Here, we analyse the epidemic in Lofa County, Liberia, lasting from March to November 2014, by reporting a comprehensive time line of events and estimating the time-varying transmission intensity using a mathematical model of Ebola transmission. Model fits to the epidemic show an alternation of peaks and troughs in transmission, consistent with highly heterogeneous spread. This is combined with an overall decline in the reproduction number of Ebola transmission from early August, coinciding with an expansion of the local Ebola treatment centre. We estimate that healthcare seeking approximately doubled over the course of the outbreak, and that isolation of those seeking healthcare reduced their reproduction number by 62% (mean estimate, 95% credible interval (CI) 59-66). Both expansion of bed availability and improved healthcare seeking contributed to ending the epidemic, highlighting the importance of community engagement alongside clinical intervention.This article is part of the themed issue 'The 2013-2016 West African Ebola epidemic: data, decision-making and disease control'.
    Publisher
    Royal Society Publishing
    URI
    http://hdl.handle.net/10144/618893
    DOI
    10.1098/rstb.2016.0302
    PubMed ID
    28396473
    Language
    en
    ISSN
    1471-2970
    ae974a485f413a2113503eed53cd6c53
    10.1098/rstb.2016.0302
    Scopus Count
    Collections
    Other Diseases

    entitlement

    Related articles

    • Ebola epidemic--Liberia, March-October 2014.
    • Authors: Nyenswah T, Fahnbulleh M, Massaquoi M, Nagbe T, Bawo L, Falla JD, Kohar H, Gasasira A, Nabeth P, Yett S, Gergonne B, Casey S, Espinosa B, McCoy A, Feldman H, Hensley L, Baily M, Fields B, Lo T, Lindblade K, Mott J, Boulanger L, Christie A, Wang S, Montgomery J, Mahoney F, Centers for Disease Control and Prevention (CDC).
    • Issue date: 2014 Nov 21
    • Community-centered responses to Ebola in urban Liberia: the view from below.
    • Authors: Abramowitz SA, McLean KE, McKune SL, Bardosh KL, Fallah M, Monger J, Tehoungue K, Omidian PA
    • Issue date: 2015 Apr
    • Impact of interventions and the incidence of ebola virus disease in Liberia-implications for future epidemics.
    • Authors: Kirsch TD, Moseson H, Massaquoi M, Nyenswah TG, Goodermote R, Rodriguez-Barraquer I, Lessler J, Cumings DA, Peters DH
    • Issue date: 2017 Mar 1
    • Challenges in responding to the ebola epidemic - four rural counties, Liberia, August-November 2014.
    • Authors: Summers A, Nyenswah TG, Montgomery JM, Neatherlin J, Tappero JW, T N, M F, M M, Centers for Disease Control and Prevention (CDC).
    • Issue date: 2014 Dec 19
    • Evidence for a decrease in transmission of Ebola virus--Lofa County, Liberia, June 8-November 1, 2014.
    • Authors: Sharma A, Heijenberg N, Peter C, Bolongei J, Reeder B, Alpha T, Sterk E, Robert H, Kurth A, Cannas A, Bocquin A, Strecker T, Logue C, Di Caro A, Pottage T, Yue C, Stoecker K, Wölfel R, Gabriel M, Günther S, Damon I, Centers for Disease Control and Prevention (CDC).
    • Issue date: 2014 Nov 21
    DSpace software (copyright © 2002 - 2021)  DuraSpace
    Quick Guide | Contact Us
    Open Repository is a service operated by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.