Neighborhood-Targeted and Case-Triggered Use of a Single Dose of Oral Cholera Vaccine in an Urban Setting: Feasibility and Vaccine Coverage
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JournalPLoS Neglected Tropical Diseases
AbstractIn June 2015, a cholera outbreak was declared in Juba, South Sudan. In addition to standard outbreak control measures, oral cholera vaccine (OCV) was proposed. As sufficient doses to cover the at-risk population were unavailable, a campaign using half the standard dosing regimen (one-dose) targeted high-risk neighborhoods and groups including neighbors of suspected cases. Here we report the operational details of this first public health use of a single-dose regimen of OCV and illustrate the feasibility of conducting highly targeted vaccination campaigns in an urban area.
PublisherPublic Library of Science