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    Apr 23, 2021
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    Tuberculosis among migrants in Bishkek, the capital of the Kyrgyz Republic

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    Goncharova et al - 2017 - ...
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    Authors
    Goncharova, O
    Denisiuk, O
    Zachariah, R
    Davtyan, K
    Nabirova, D
    Acosta, C
    Kadyrov, A
    Issue Date
    2017-09-21
    Submitted date
    2018-05-16
    
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    Journal
    Public Health Action
    Abstract
    Setting: Twenty-two first-line, two second-line and one tertiary health facility in Bishkek, the capital of Kyrgyzstan. Objectives: Among migrants, a marginalised population at risk for acquiring and transmitting tuberculosis (TB), we determined the proportion with TB among all registered TB cases. For those registered at primary-level facilities, we then reported on their demographic and clinical profiles and TB treatment outcomes. Design: This was a retrospective cohort analysis of 2012-2013 programme data. Results: Of 2153 TB patients registered in all health facilities, 969 (45%) were migrants, of whom 454 were registered in first-line facilities. Of these, 27% were cross-border migrants, 50% had infectious TB and 12% had drug-resistant TB. Treatment success was 74% for new cases and 44% for retreatment TB (the World Health Organization target is ⩾85%). Failure in new and retreatment TB patients was respectively 8% and 25%. Twenty-six individuals started on a first-line anti-tuberculosis regimen failed due to multidrug-resistant TB. Eight (25%) of 32 individuals on a retreatment TB regimen also failed. Loss to follow-up was 10% for new and 19% for retreatment TB. Conclusion: Migrants constituted almost half of all TB patients, drug resistance is prevalent and treatment outcomes unsatisfactory. Fostering inter-country collaboration and prioritising rapid TB diagnostics (Xpert® MTB/RIF) and innovative ways forward for improving treatment outcomes is urgent.
    Publisher
    International Union Against Tuberculosis and Lung Disease
    URI
    http://hdl.handle.net/10144/619132
    DOI
    10.5588/pha.17.0002
    PubMed ID
    29201657
    Language
    en
    ISSN
    2220-8372
    ae974a485f413a2113503eed53cd6c53
    10.5588/pha.17.0002
    Scopus Count
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