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    Apr 19, 2021
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    Cryptococcal antigen screening by lay cadres using a rapid test at the point of care: A feasibility study in rural Lesotho

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    Rick et al - 2017 - Cryptococcal ...
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    Authors
    Rick, F
    Niyibizi, AA
    Shroufi, A
    Onami, K
    Steele, SJ
    Kuleile, M
    Muleya, I
    Chiller, T
    Walker, T
    Van Cutsem, G
    Issue Date
    2017-09-06
    Submitted date
    2018-05-16
    
    Metadata
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    Journal
    PLoS ONE
    Abstract
    Cryptococcal meningitis is one of the leading causes of death among people with HIV in Africa, primarily due to delayed presentation, poor availability and high cost of treatment. Routine cryptococcal antigen (CrAg) screening of patients with a CD4 count less than 100 cells/mm3, followed by pre-emptive therapy if positive, might reduce mortality in high prevalence settings. Using the cryptococcal antigen (CrAg) lateral flow assay (LFA), screening is possible at the point of care (POC). However, critical shortages of health staff may limit adoption. This study investigates the feasibility of lay counsellors conducting CrAg LFA screening in rural primary care clinics in Lesotho.
    Publisher
    Public Library of Science
    URI
    http://hdl.handle.net/10144/619134
    DOI
    10.1371/journal.pone.0183656
    PubMed ID
    28877182
    Language
    en
    ISSN
    1932-6203
    ae974a485f413a2113503eed53cd6c53
    10.1371/journal.pone.0183656
    Scopus Count
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    Other Diseases

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