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    Jan 16, 2021
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    The initial effectiveness of liposomal amphotericin B (AmBisome) and miltefosine combination for treatment of visceral leishmaniasis in HIV co-infected patients in Ethiopia: A retrospective cohort study

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    Name:
    Abongomera C et al - 2018 - The ...
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    Authors
    Abongomera, C
    Diro, E
    de Lima Pereira, A
    Buyze, J
    Stille, K
    Ahmed, F
    van Griensven, J
    Ritmeijer, K
    Issue Date
    2018-05-25
    Submitted date
    2018-06-04
    
    Metadata
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    Journal
    PLoS Neglected Tropical Diseases
    Abstract
    North-west Ethiopia faces the highest burden world-wide of visceral leishmaniasis (VL) and HIV co-infection. VL-HIV co-infected patients have higher (initial) parasitological failure and relapse rates than HIV-negative VL patients. Whereas secondary prophylaxis reduces the relapse rate, parasitological failure rates remain high with the available antileishmanial drugs, especially when administered as monotherapy. We aimed to determine the initial effectiveness (parasitologically-confirmed cure) of a combination of liposomal amphotericin B (AmBisome) and miltefosine for treatment of VL in HIV co-infected patients.
    Publisher
    Public Library of Science
    URI
    http://hdl.handle.net/10144/619175
    DOI
    10.1371/journal.pntd.0006527
    PubMed ID
    29799869
    Language
    en
    ISSN
    1935-2735
    ae974a485f413a2113503eed53cd6c53
    10.1371/journal.pntd.0006527
    Scopus Count
    Collections
    HIV/AIDS

    entitlement

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