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dc.contributor.authorBoulle, A
dc.contributor.authorTeck, R
dc.contributor.authorLukhele, N
dc.contributor.authorRusch, B
dc.contributor.authorTelnov, A
dc.contributor.authorMabhena, E
dc.contributor.authorPasipamire, L
dc.contributor.authorCiglenecki, I
dc.contributor.authorSchomaker, M
dc.contributor.authorKerschberger, B
dc.date.accessioned2019-04-19T18:50:10Z
dc.date.available2019-04-19T18:50:10Z
dc.date.issued2019-04-01
dc.date.submitted2019-04-19
dc.identifier.issn1365-3156
dc.identifier.pmid30938037
dc.identifier.doi10.1111/tmi.13234
dc.identifier.urihttp://hdl.handle.net/10144/619365
dc.description.abstractTo assess long-term antiretroviral therapy (ART) outcomes during rapid HIV programme expansion in the public sector of Eswatini (formerly Swaziland). This is a retrospectively established cohort of HIV-positive adults (≥16 years) who started first-line ART in 25 health facilities in Shiselweni (Eswatini) between 01/2006 and 12/2014. Temporal trends in ART attrition, treatment expansion and ART coverage were described over 9 years. We used flexible parametric survival models to assess the relationship between time to ART attrition and covariates. Of 24 772 ART initiations, 6% (n = 1488) occurred in 2006, vs. 13% (n = 3192) in 2014. Between these years, median CD4 cell count at ART initiation increased (113-265 cells/mm Programmatic outcomes improved during large expansion of the treatment cohort and increased ART coverage. Changes in ART programming may have contributed to better outcomes.en_US
dc.language.isoenen_US
dc.publisherJohn Wiley & Sonsen_US
dc.rightsWith thanks to John Wiley & Sons.en_US
dc.subjectART expansion
dc.subjectEswatini
dc.subjectSwaziland
dc.subjectattrition
dc.subjecttemporal trends
dc.titleProgrammatic outcomes and impact of rapid public sector antiretroviral therapy expansion in adults prior to introduction of the WHO treat-all approach in rural Eswatini.en_US
dc.identifier.journalTropical Medicine & International Healthen_US
dc.source.journaltitleTropical medicine & international health : TM & IH
refterms.dateFOA2019-04-19T18:50:11Z


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