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    Jan 26, 2021
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    Bedaquiline overdose: A case report

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    Telnov et al - 2019 - Bedaquiline ...
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    Authors
    Telnov, O
    Alvarez, V
    Gragila, E
    Molfino, L
    du Cros, P
    Rich, M
    Issue Date
    2019-04-02
    Submitted date
    2019-04-08
    
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    Journal
    International Journal of Infectious Disease
    Abstract
    We present a case report describing outcomes in a 21 year old HIV-negative man who received treatment with bedaquiline. Due to error, dosage received comprised 4 pills of 100 mg every second day in the 60 days following the first two weeks of 4 pills of 100 mg every day. On detection, treatment was continued as per standard dosing of 200 mg given three times per week, with enhanced monitoring of ECG and liver function. The man was asymptomatic, with no signs of jaundice, abdominal pain, or abnormal heart rhythm. Toxic effects at this dosage were therefore not observed.
    Publisher
    Elsevier
    URI
    http://hdl.handle.net/10144/619367
    Language
    en
    Collections
    TB

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