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    Jan 19, 2021
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    Breast Tuberculosis in Women: A Systematic Review

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    Authors
    Quaglio, G
    Pizzol, D
    Isaakidis, P
    Bortolani, A
    Tognon, F
    Marotta, C
    Di Gennaro, F
    Putoto, G
    Olliaro, P
    Issue Date
    2019-05-20
    Submitted date
    2019-06-20
    
    Metadata
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    Journal
    The American Journal of Tropical Medicine and Hygiene
    Abstract
    Breast tuberculosis (TB) is rarely reported and poorly described. This review aims to update the existing literature on risk factors, clinical presentations, constitutional symptoms, diagnostic procedures, and medical and surgical treatments for breast TB. In all, 1,478 cases of breast TB were collected. Previous history of TB was reported in 19% of cases. The most common clinical appearance of the lesion was breast lump (75%). The most common associated finding was axillary lymphadenitis (33%) followed by sinus or fistula (24%). The most common symptoms were pain and fever, reported in 42% and 28% of cases, respectively. The most used diagnostic method was fine-needle aspiration cytology (32%), followed by biopsy (27%), acid-fast bacteria Ziehl–Neelsen stain (26%), culture (13%), and polymerase chain reaction (2%). These tested positive in 64%, 93%, 27%, 26%, and 58% of cases, respectively. The majority (69%) of patients received a 6-month anti-TB treatment (isoniazid, rifampicin, pyrazinamide, and ethambutol). Surgery consisted of excision in 39% of cases, drainage in 23%, and mastectomy in 5%. The great majority of patients had a positive outcome. It often mimics breast cancer, which makes it difficult to diagnose. Most patients, when diagnosed in time, respond to antitubercular therapy alone.
    Publisher
    American Society of Tropical Medicine and Hygiene
    URI
    http://hdl.handle.net/10144/619396
    Language
    en
    Collections
    Womens/Reproductive Health

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