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dc.contributor.authorKanapathipillai, R
dc.contributor.authorMalou, N
dc.contributor.authorHopman, J
dc.contributor.authorBowman, C
dc.contributor.authorYousef, N
dc.contributor.authorMichel, J
dc.contributor.authorHussein, N
dc.contributor.authorHerard, P
dc.contributor.authorOusley, J
dc.contributor.authorMills, C
dc.contributor.authorSeguin, C
dc.contributor.authorSaim, M
dc.date.accessioned2019-06-26T14:30:28Z
dc.date.available2019-06-26T14:30:28Z
dc.date.issued2019-04-10
dc.date.submitted2019-05-10
dc.identifier.urihttp://hdl.handle.net/10144/619402
dc.description.abstractMe´decins Sans Frontie`res (MSF) has designed context-adapted antibiotic resistance (ABR) responses in countries across the Middle East. There, some health systems have been severely damaged by conflict resulting in delayed access to care, crowded facilities and supply shortages. Microbiological surveillance data are rarely available, but when MSF laboratories are installed we often find MDR bacteria at alarming levels.1 In MSF’s regional hospital in Jordan, where surgical patients have often had multiple surgeries in field hospitals before reaching definitive care (often four or more), MSF microbiological data analysis reveals that, among Enterobacteriaceae isolates, third-generation cephalosporin and carbapenem resistance is 86.2% and 4.3%, respectively; MRSA prevalence among Staphylococcus aureus is 60.5%; and resistance types and rates are similar in patients originating from Yemen, Syria and Iraq.1–3 These trends compel MSF to aggressively prevent and diagnose ABR in Jordan, providing ABR lessons that inform the antibiotic choices, microbiological diagnostics and anti-ABR strategies in other Middle Eastern MSF trauma projects (such as Yemen and Gaza). As a result, MSF has created a multifaceted, context-adapted, field experience-based, approach to ABR in hospitals in Middle Eastern conflict settings. We focus on three pillars: (1) infection prevention and control (IPC); (2) microbiology and surveillance; and (3) antibiotic stewardship.en_US
dc.language.isoenen_US
dc.publisherOxford University Pressen_US
dc.rightsWith thanks to Oxford University Press.en_US
dc.titleAntibiotic resistance in conflict settings: lessons learned in the Middle Easten_US
dc.identifier.journalJournal of Antimicrobial Chemotherapyen_US
refterms.dateFOA2019-06-26T14:30:28Z


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