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    Jan 16, 2021
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    GeneXpert and Community Health Workers Supported Patient Tracing for Tuberculosis Diagnosis in Conflict-Affected Border Areas in India.

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    Authors
    Das, M
    Pasupuleti, D
    Rao, S
    Sloan, S
    Mansoor, H
    Kalon, S
    Hossain, F
    Ferlazzo, G
    Isaakidis, P
    Issue Date
    2019-12-21
    Submitted date
    2020-01-23
    
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    Journal
    Tropical Medicine and Infectious Disease
    Abstract
    Médecins Sans Frontières (MSF) has been providing diagnosis and treatment for patients with tuberculosis (TB) via mobile clinics in conflict-affected border areas of Chhattisgarh, India since 2009. The study objectives were to determine the proportion of patients diagnosed with TB and those who were lost-to-follow-up (LTFU) prior to treatment initiation among patients with presumptive TB between April 2015 and August 2018. The study also compared bacteriological confirmation and pretreatment LTFU during two time periods: a) April 2015–August 2016 and b) April 2017–August 2018 (before and after the introduction of GeneXpert as a first diagnostic test). Community health workers (CHW) supported patient tracing. This study was a retrospective analysis of routine program data. Among 1042 patients with presumptive TB, 376 (36%) were diagnosed with TB. Of presumptive TB patients, the pretreatment LTFU was 7%. Upon comparing the two time-periods, bacteriological confirmation increased from 20% to 33%, while pretreatment LTFU decreased from 11% to 4%. TB diagnosis with GeneXpert as the first diagnostic test and CHW-supported patient tracing in a mobile-clinic model of care shows feasibility for replication in similar conflict-affected, hard to reach areas.
    Publisher
    MDPI AG
    URI
    http://hdl.handle.net/10144/619581
    DOI
    10.3390/tropicalmed5010001
    PubMed ID
    31877818
    Language
    en
    ISSN
    2414-6366
    ae974a485f413a2113503eed53cd6c53
    10.3390/tropicalmed5010001
    Scopus Count
    Collections
    TB

    entitlement

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