• Login
    View Item 
    •   Home
    • 1 Published Research and Commentary
    • Operational Research Courses
    • View Item
    •   Home
    • 1 Published Research and Commentary
    • Operational Research Courses
    • View Item
    Jan 20, 2021
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of MSFTitleAuthorsSubjectsPublisherJournalThis CollectionTitleAuthorsSubjectsPublisherJournal

    Clinical features and treatment outcomes of visceral leishmaniasis patients admitted to three centers in Oromia, Ethiopia

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Thumbnail
    Name:
    Tekalign et al 2020 Clinical ...
    Size:
    520.5Kb
    Format:
    PDF
    Download
    Authors
    Tekalign, S
    Adera, C
    den Boer, M
    Miecha, H
    Zewde, A
    Mulugeta, D
    Bishawu, T
    Birru, W
    Lema, A
    Sahlu, T
    Alves, F
    Manzi, M
    Takarinda, K
    Van Griensven, J
    Show allShow less
    Issue Date
    2020-06-30
    Submitted date
    2020-07-25
    
    Metadata
    Show full item record
    Journal
    Journal of Infection in Developing Countries
    Abstract
    Introduction: In three health care facilities in the Oromia region, the aim of this study is to report on 1) the number of VL cases registered over time (2013-2018) and 2) the clinical profile, type of treatment used and response to treatment. Methodology: A retrospective cohort study was conducted among all VL cases admitted with a diagnosis of VL. Results: A total of 434 VL cases were registered at the three health facilities, but patient files were available for only 188. Most (51.6%) were children and only three presented with VL relapse. 78 (41.5%) of the 188 patients presented within one month of symptom onset. Concurrent severe acute malnutrition (27.1%), tuberculosis (6.4%) and malaria (6.4%) were common. There were only two cases with HIV coinfection. Fourty-three percent were treated with antimonials, 34% with antimonials combined with paromomycin and 23% with AmBisome. Amongst the 188 patients with patient files there were no deaths and one treatment failure. Six months outcome data were however missing for all. Aggregated data from the 434 VL cases reported three deaths, two treatment failures and one relapse. Conclusions: Children were most commonly affected, suggesting long-term endemicity. While short-term outcomes are encouraging, long-term follow-up data are required.
    Publisher
    Journal of Infection in Developing Countries
    URI
    http://hdl.handle.net/10144/619722
    DOI
    10.3855/jidc.11731
    PubMed ID
    32614795
    Type
    Article
    Language
    en
    EISSN
    1972-2680
    ae974a485f413a2113503eed53cd6c53
    10.3855/jidc.11731
    Scopus Count
    Collections
    Operational Research Courses

    entitlement

    Related articles

    • The initial effectiveness of liposomal amphotericin B (AmBisome) and miltefosine combination for treatment of visceral leishmaniasis in HIV co-infected patients in Ethiopia: A retrospective cohort study.
    • Authors: Abongomera C, Diro E, de Lima Pereira A, Buyze J, Stille K, Ahmed F, van Griensven J, Ritmeijer K
    • Issue date: 2018 May
    • Visceral leishmaniasis and HIV co-infection in Bihar, India: long-term effectiveness and treatment outcomes with liposomal amphotericin B (AmBisome).
    • Authors: Burza S, Mahajan R, Sinha PK, van Griensven J, Pandey K, Lima MA, Sanz MG, Sunyoto T, Kumar S, Mitra G, Kumar R, Verma N, Das P
    • Issue date: 2014 Aug
    • Liposomal amphotericin B for complicated visceral leishmaniasis (kala-azar) in eastern Sudan: how effective is treatment for this neglected disease?
    • Authors: Salih NA, van Griensven J, Chappuis F, Antierens A, Mumina A, Hammam O, Boulle P, Alirol E, Alnour M, Elhag MS, Manzi M, Kizito W, Zachariah R
    • Issue date: 2014 Feb
    • Limited effectiveness of high-dose liposomal amphotericin B (AmBisome) for treatment of visceral leishmaniasis in an Ethiopian population with high HIV prevalence.
    • Authors: Ritmeijer K, ter Horst R, Chane S, Aderie EM, Piening T, Collin SM, Davidson RN
    • Issue date: 2011 Dec
    • Visceral leishmaniasis treatment outcome and its determinants in northwest Ethiopia.
    • Authors: Welay GM, Alene KA, Dachew BA
    • Issue date: 2016
    DSpace software (copyright © 2002 - 2021)  DuraSpace
    Quick Guide | Contact Us
    Open Repository is a service operated by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.