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dc.contributor.authorFarley, ES
dc.contributor.authorAmirtharajah, M
dc.contributor.authorWinters, RD
dc.contributor.authorTaiwo, AO
dc.contributor.authorOyemakinda, MJ
dc.contributor.authorFosto, A
dc.contributor.authorTorhee, LA
dc.contributor.authorMehta, UC
dc.contributor.authorBil, KA
dc.contributor.authorLenglet, AD
dc.date.accessioned2020-10-21T16:43:13Z
dc.date.available2020-10-21T16:43:13Z
dc.date.issued2020-08-12
dc.date.submitted2020-10-06
dc.identifier.pmid32785671
dc.identifier.doi10.1093/trstmh/traa061
dc.identifier.urihttp://hdl.handle.net/10144/619740
dc.description.abstractBackground: Noma is a rapidly progressing infection of the oral cavity frequently resulting in severe facial disfigurement. We present a case series of noma patients surgically treated in northwest Nigeria. Methods: A retrospective analysis of routinely collected data (demographics, diagnosis and surgical procedures undergone) and in-person follow-up assessments (anthropometry, mouth opening and quality of life measurements) were conducted with patients who had surgery >6 mo prior to data collection. Results: Of the 37 patients included, 21 (56.8%) were male and 22 (62.9%) were aged >6 y. The median number of months between last surgery and follow-up was 18 (IQR 13, 25) mo. At admission, the most severely affected anatomical area was the outer cheek (n = 9; 36.0% of patients had lost between 26% and 50%). The most frequent surgical procedures were the deltopectoral flap (n = 16; 43.2%) and trismus release (n = 12; 32.4%). For the eight trismus-release patients where mouth opening was documented at admission, all had a mouth opening of 0-20 mm at follow-up. All patients reported that the surgery had improved their quality of life. Conclusions: Following their last surgical intervention, noma patients do experience some improvements in their quality of life, but debilitating long-term sequelae persist.en_US
dc.language.isoenen_US
dc.publisherOxford University Pressen_US
dc.rightsWith thanks to Oxford University Press.en_US
dc.subjectcancrum oris
dc.subjectnoma
dc.subjectoutcomes
dc.titleOutcomes at 18 mo of 37 noma (cancrum oris) cases surgically treated at the Noma Children's Hospital, Sokoto, Nigeria.en_US
dc.typeArticle
dc.identifier.eissn1878-3503
dc.identifier.journalTransactions of the Royal Society of Tropical Medicine and Hygieneen_US
dc.source.journaltitleTransactions of the Royal Society of Tropical Medicine and Hygiene
refterms.dateFOA2020-10-21T16:43:14Z
dc.source.countryEngland


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