Genetic heterogeneity of hepatitis E virus in Darfur, Sudan, and neighboring Chad.
Affiliation
National Reference Centre for Hepatitis E, Teaching Military Hospital Val de Grâce, Paris, France. en.biol-vdg@filnet.frIssue Date
2005-12
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Journal of Medical VirologyAbstract
The within-outbreak diversity of hepatitis E virus (HEV) was studied during the outbreak of hepatitis E that occurred in Sudan in 2004. Specimens were collected from internally displaced persons living in a Sudanese refugee camp and two camps implanted in Chad. A comparison of the sequences in the ORF2 region of 23 Sudanese isolates and five HEV samples from the two Chadian camps displayed a high similarity (>99.7%) to strains belonging to Genotype 1. But four isolates collected in one of the Chadian camps were close to Genotype 2. Circulation of divergent strains argues for possible multiple sources of infection.PubMed ID
16254969Type
ArticleLanguage
enISSN
0146-6615Sponsors
Epicentreae974a485f413a2113503eed53cd6c53
10.1002/jmv.20487
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