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dc.contributor.authorTrollip, A P
dc.contributor.authorAlbert, H
dc.contributor.authorMole, R
dc.contributor.authorMarshall, T
dc.contributor.authorvan Cutsem, G
dc.contributor.authorCoetzee, D
dc.date.accessioned2009-07-23T10:31:21Z
dc.date.available2009-07-23T10:31:21Z
dc.date.issued2009-06
dc.identifier.citationPerformance of FASTPlaqueTB and a modified protocol in a high HIV prevalence community in South Africa. 2009, 13 (6):791-3 Int. J. Tuberc. Lung Dis.en
dc.identifier.issn1027-3719
dc.identifier.pmid19460258
dc.identifier.urihttp://hdl.handle.net/10144/75176
dc.description.abstractModifications in the FASTPlaqueTB test protocol have resulted in an increase in the analytical limits of detection. This study investigated whether the performance of a modified prototype was able to increase the detection of smear-negative, culture-positive sputum samples as compared to the first generation FASTPlaqueTB test. Modifications to the FASTPlaqueTB did result in increased detection of smear-negative samples, but this was associated with a decrease in the specificity of the test. Before the FASTPlaqueTB can be considered as a viable replacement for smear microscopy and culture for the identification of tuberculosis, further work is required to resolve the performance issues identified in this study.
dc.language.isoenen
dc.rightsArchived with thanks to The International Journal of Tuberculosis and Lung Disease : the official journal of the International Union against Tuberculosis and Lung Diseaseen
dc.subject.meshComorbidityen
dc.subject.meshHIV Infectionsen
dc.subject.meshHumansen
dc.subject.meshMicrobial Sensitivity Testsen
dc.subject.meshPredictive Value of Testsen
dc.subject.meshSouth Africaen
dc.subject.meshSputumen
dc.subject.meshTuberculosis, Pulmonaryen
dc.titlePerformance of FASTPlaqueTB and a modified protocol in a high HIV prevalence community in South Africa.en
dc.contributor.departmentBiotec Laboratories South Africa Ltd, Cape Town, South Africa. andre.trollip@bioteclabs.co.zaen
dc.identifier.journalInternational Journal of Tuberculosis and Lung Diseaseen
refterms.dateFOA2019-03-04T14:25:46Z
html.description.abstractModifications in the FASTPlaqueTB test protocol have resulted in an increase in the analytical limits of detection. This study investigated whether the performance of a modified prototype was able to increase the detection of smear-negative, culture-positive sputum samples as compared to the first generation FASTPlaqueTB test. Modifications to the FASTPlaqueTB did result in increased detection of smear-negative samples, but this was associated with a decrease in the specificity of the test. Before the FASTPlaqueTB can be considered as a viable replacement for smear microscopy and culture for the identification of tuberculosis, further work is required to resolve the performance issues identified in this study.


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