Natural history of a visceral leishmaniasis outbreak in highland Ethiopia
Name:
Herrero_VL-Ethiopia_AJTMH-2009.pdf
Size:
642.4Kb
Format:
PDF
Description:
Main article
Authors
Herrero, MOrfanos, G
Argaw, D
Mulugeta, A
Aparicio, P
Parreño, F
Bernal, O
Rubens, D
Pedraza, J
Lima, M A
Flevaud, L
Palma, P P
Bashaye, S
Alvar, J
Bern, C
Affiliation
Disease Prevention and Control Programmes, World Health Organization, Addis Ababa, Ethiopia; Médecins Sans Frontières-Ethiopia, Operational Centre Barcelona-Athens, Addis Zemen, Ethiopia; Department for the Control of Neglected Tropical Diseases, Leishmaniasis Control Program, World Health Organization, Geneva, Switzerland; National Centre of Tropical Medicine, Instituto de Salud Carlos III, Madrid, Spain; Médecins Sans Frontières, Medical Department, Operational Centre Barcelona-Athens (OCBA), Barcelona, Spain; Malaria and Other Vector Borne Diseases, Prevention and Control Program, Ministry of Health, Addis Ababa, Ethiopia; Division of Parasitic Diseases, National Center for Zoonotic, Vector-Borne and Enteric Diseases, Centers for Disease Control and Prevention, Atlanta, GeorgiaIssue Date
2009-09-01Submitted date
2009-08-27
Metadata
Show full item recordAbstract
In May 2005, visceral leishmaniasis (VL) was recognized for the first time in Libo Kemken, Ethiopia, a highland region where only few cases had been reported before. We analyzed records of VL patients treated from May 25, 2005 to December 13, 2007 by the only VL treatment center in the area, maintained by Médecins Sans Frontières-Ethiopia, Operational Center Barcelona-Athens. The median age was 18 years; 77.6% were male. The overall case fatality rate was 4%, but adults 45 years or older were five times as likely to die as 5-29 year olds. Other factors associated with increased mortality included HIV infection, edema, severe malnutrition, pneumonia, tuberculosis, and vomiting. The VL epidemic expanded rapidly over a several-year period, culminating in an epidemic peak in the last third of 2005, spread over two districts, and transformed into a sustained endemic situation by 2007.PubMed ID
19706898Additional Links
http://www.ajtmh.org/cgi/content/abstract/81/3/373Type
ArticleLanguage
enISSN
1476-1645Collections
Related articles
- Risk factors for in-hospital mortality of visceral leishmaniasis patients in eastern Uganda.
- Authors: Mueller Y, Mbulamberi DB, Odermatt P, Hoffmann A, Loutan L, Chappuis F
- Issue date: 2009 Aug
- Kala-azar outbreak in Libo Kemkem, Ethiopia: epidemiologic and parasitologic assessment.
- Authors: Alvar J, Bashaye S, Argaw D, Cruz I, Aparicio P, Kassa A, Orfanos G, Parreño F, Babaniyi O, Gudeta N, Cañavate C, Bern C
- Issue date: 2007 Aug
- Clinical characteristics and treatment outcome of patients with visceral leishmaniasis and HIV co-infection in northwest Ethiopia.
- Authors: Hurissa Z, Gebre-Silassie S, Hailu W, Tefera T, Lalloo DG, Cuevas LE, Hailu A
- Issue date: 2010 Jul
- Visceral leishmaniasis in Nepal during 1980-2006.
- Authors: Joshi DD, Sharma M, Bhandari S
- Issue date: 2006 Mar
- Prevalence of malnutrition and associated risk factors among adult visceral leishmaniasis patients in Northwest Ethiopia: a cross sectional study.
- Authors: Mengesha B, Endris M, Takele Y, Mekonnen K, Tadesse T, Feleke A, Diro E
- Issue date: 2014 Feb 4