Mortality reduction associated with HIV/AIDS care and antiretroviral treatment in rural Malawi: evidence from registers, coffin sales and funerals.
dc.contributor.author | Mwagomba, Beatrice | |
dc.contributor.author | Zachariah, Rony | |
dc.contributor.author | Massaquoi, Moses | |
dc.contributor.author | Misindi, Dalitso | |
dc.contributor.author | Manzi, Marcel | |
dc.contributor.author | Mandere, Bester C | |
dc.contributor.author | Bemelmans, Marielle | |
dc.contributor.author | Philips, Mit | |
dc.contributor.author | Kamoto, Kelita | |
dc.contributor.author | Schouten, Eric J | |
dc.contributor.author | Harries, A D | |
dc.date.accessioned | 2010-05-19T18:42:57Z | |
dc.date.available | 2010-05-19T18:42:57Z | |
dc.date.issued | 2010-05 | |
dc.identifier.citation | Mortality reduction associated with HIV/AIDS care and antiretroviral treatment in rural Malawi: evidence from registers, coffin sales and funerals. 2010, 5 (5):e10452 PLoS ONE | en |
dc.identifier.issn | 1932-6203 | |
dc.identifier.pmid | 20454611 | |
dc.identifier.doi | 10.1371/journal.pone.0010452 | |
dc.identifier.uri | http://hdl.handle.net/10144/99348 | |
dc.description.abstract | BACKGROUND: To report on the trend in all-cause mortality in a rural district of Malawi that has successfully scaled-up HIV/AIDS care including antiretroviral treatment (ART) to its population, through corroborative evidence from a) registered deaths at traditional authorities (TAs), b) coffin sales and c) church funerals. METHODS AND FINDINGS: Retrospective study in 5 of 12 TAs (covering approximately 50% of the population) during the period 2000-2007. A total of 210 villages, 24 coffin workshops and 23 churches were included. There were a total of 18,473 registered deaths at TAs, 15781 coffins sold, and 2762 church funerals. Between 2000 and 2007, there was a highly significant linear downward trend in death rates, sale of coffins and church funerals (X(2) for linear trend: 338.4 P<0.0001, 989 P<0.0001 and 197, P<0.0001 respectively). Using data from TAs as the most reliable source of data on deaths, overall death rate reduction was 37% (95% CI:33-40) for the period. The mean annual incremental death rate reduction was 0.52/1000/year. Death rates decreased over time as the percentage of people living with HIV/AIDS enrolled into care and ART increased. Extrapolating these data to the entire district population, an estimated 10,156 (95% CI: 9786-10259) deaths would have been averted during the 8-year period. CONCLUSIONS: Registered deaths at traditional authorities, the sale of coffins and church funerals showed a significant downward trend over a 8-year period which we believe was associated with the scaling up HIV/AIDS care and ART. | |
dc.language.iso | en | en |
dc.rights | Published by Public Library of Science, [url]http://www.plosone.org/[/url] Archived on this site by Open Access permission | en |
dc.title | Mortality reduction associated with HIV/AIDS care and antiretroviral treatment in rural Malawi: evidence from registers, coffin sales and funerals. | en |
dc.contributor.department | Thyolo District Health Services, Ministry of Health and Population, Thyolo, Malawi. | en |
dc.identifier.journal | PloS One | en |
refterms.dateFOA | 2019-03-04T15:41:15Z | |
html.description.abstract | BACKGROUND: To report on the trend in all-cause mortality in a rural district of Malawi that has successfully scaled-up HIV/AIDS care including antiretroviral treatment (ART) to its population, through corroborative evidence from a) registered deaths at traditional authorities (TAs), b) coffin sales and c) church funerals. METHODS AND FINDINGS: Retrospective study in 5 of 12 TAs (covering approximately 50% of the population) during the period 2000-2007. A total of 210 villages, 24 coffin workshops and 23 churches were included. There were a total of 18,473 registered deaths at TAs, 15781 coffins sold, and 2762 church funerals. Between 2000 and 2007, there was a highly significant linear downward trend in death rates, sale of coffins and church funerals (X(2) for linear trend: 338.4 P<0.0001, 989 P<0.0001 and 197, P<0.0001 respectively). Using data from TAs as the most reliable source of data on deaths, overall death rate reduction was 37% (95% CI:33-40) for the period. The mean annual incremental death rate reduction was 0.52/1000/year. Death rates decreased over time as the percentage of people living with HIV/AIDS enrolled into care and ART increased. Extrapolating these data to the entire district population, an estimated 10,156 (95% CI: 9786-10259) deaths would have been averted during the 8-year period. CONCLUSIONS: Registered deaths at traditional authorities, the sale of coffins and church funerals showed a significant downward trend over a 8-year period which we believe was associated with the scaling up HIV/AIDS care and ART. |